Anti-IL17RD 抗体 (ab111553)

製品の概要

• 製品名
  Anti-IL17RD antibody
  IL17RD 一次抗体 製品一覧
• 製品の詳細
  Rabbit polyclonal to IL17RD
• アプリケーション
  適用あり: WB, ICC/IFmore details
• 種交差性
  交差種: Human
  交差が予測される動物種: Mouse, Rat, Chicken
• 免疫原

  Recombinant protein fragment containing a sequence corresponding to a region within amino acids 1 and 209 (Q8NFM7) of IL17 Receptor D

• ポジティブ･コントロール
  • NT2D1, IMR32 whole cell lysate, U87-MG, MCF-7 cells.

製品の特性

• 製品の状態
  Liquid
• 保存方法
  Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• バッファー
  pH: 7.00
  Preservative: 0.01% Thimerosal (merthiolate)
  Constituents: 78.99% PBS, 1% BSA, 20% Glycerol
• Concentration information loading...
• 精製度
  Immunogen affinity purified
• ポリ/モノ
  ポリクローナル
• アイソタイプ
  IgG
• 研究分野
  • Immunology
  • Innate Immunity
  • Cytokines
  • Interleukins

  • Signal Transduction
  • Protein Phosphorylation
  • Ser / Thr Kinases
  • MAPK Pathway

  • Signal Transduction
  • Signaling Pathway
  • G Protein Signaling
  • Small G Proteins
  • Ras Family

  • Signal Transduction
  • Protein Phosphorylation
  • Tyrosine Kinases
  • Receptor Tyrosine Kinases

  • Signal Transduction
  • Growth Factors/Hormones
  • FGF

  • Cancer
  • Oncoproteins/suppressors
  • Tumor suppressors
  • Other

関連製品

• Compatible Secondaries
  • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
  • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)

アプリケーション

ターゲット情報

• 機能
  Feedback inhibitor of fibroblast growth factor mediated Ras-MAPK signaling and ERK activation. May inhibit FGF-induced FGFR1 tyrosine phosphorylation. Regulates the nuclear ERK signaling pathway by spatially blocking nuclear translocation of activated ERK without inhibiting cytoplasmic phosphorylation of ERK. Mediates JNK activation and may be involved in apoptosis.
• 組織特異性
  Expressed in umbilical vein endothelial cells and in several highly vascularized tissues such as kidney, colon, skeletal muscle, heart and small intestine. Highly expressed in ductal epithelial cells of salivary glands, seminal vesicles and the collecting tubules of the kidney. Isoform 1 is also highly expressed in both fetal and adult brain, pituarity, tonsils, spleen, adenoids, fetal kidney, liver, testes and ovary. Isoform 1 is also expressed at moderate levels in primary aortic endothelial cells and adrenal medulla, and at low levels in adrenal cortex. Isoform 4 is specifically and highly expressed in pituitary, fetal brain and umbilical vein endothelial cells.
• 細胞内局在
  Cytoplasm and Golgi apparatus membrane. Cell membrane. Predominantly associated with the Golgi apparatus and is partially translocated to the plasma membrane upon stimulation.

• Target information above from: UniProt accession Q8NFM7 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• 参照データベース
  • Entrez Gene: 54756 Human
  • Entrez Gene: 171463 Mouse
  • Entrez Gene: 498576 Rat
  • Omim: 606807 Human
  • SwissProt: Q8NFM7 Human
  • SwissProt: Q8JZL1 Mouse
  • Unigene: 150725 Human
  • Unigene: 206726 Mouse
• 別名
  • DKFZp434N1928 antibody
  • FLJ35755 antibody
  • hSef antibody

  • I17RD_HUMAN antibody
  • IL 17 receptor D antibody
  • IL 17RD antibody
  • IL-17 receptor D antibody
  • IL-17RD antibody
  • IL17 receptor D antibody
  • il17rd antibody
  • IL17Rhom antibody
  • IL17RLM antibody
  • Interleukin 17 receptor D antibody
  • Interleukin 17 receptor like protein antibody
  • Interleukin-17 receptor D antibody
  • Interleukin-17 receptor-like protein antibody
  • Interleukin17 receptor D antibody
  • MGC133309 antibody
  • SEF antibody
  • Sef homolog antibody

  see all

プロトコール

• Western blot protocols
• Immunocytochemistry & immunofluorescence protocols