製品の概要

  • 製品名
    Anti-IL17F antibody [H17F10A7]
    IL17F 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [H17F10A7] to IL17F
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant Human IL17F

  • ポジティブ・コントロール
    • Activated Th17 cells.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab90878 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
  • 追加情報
    WB: Use at a concentration of 1 - 2 µg/ml. Predicted molecular weight: 18 kDa.
    It is recommended that ab90878 be used under reducing conditions only.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能
      Ligand for IL17RA and IL17RC (PubMed:17911633). The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC (PubMed:18684971). Involved in stimulating the production of other cytokines such as IL6, IL8 and CSF2, and in regulation of cartilage matrix turnover (PubMed:11591732, PubMed:11591768, PubMed:11574464). Also involved in stimulating the proliferation of peripheral blood mononuclear cells and T-cells and in inhibition of angiogenesis (PubMed:11591732). Plays a role in the induction of neutrophilia in the lungs and in the exacerbation of antigen-induced pulmonary allergic inflammation.
    • 組織特異性
      Expressed in activated, but not resting, CD4+ T-cells and activated monocytes.
    • 関連疾患
      Candidiasis, familial, 6
    • 配列類似性
      Belongs to the IL-17 family.
    • 細胞内局在
      Secreted.
    • Information by UniProt
    • 参照データベース
    • 別名
      • CANDF6 antibody
      • Cytokine ML 1 antibody
      • Cytokine ML-1 antibody
      • IL 17F antibody
      • IL 24 antibody
      • IL-17F antibody
      • Il17f antibody
      • IL17F_HUMAN antibody
      • Interleukin 17F antibody
      • Interleukin 24 antibody
      • Interleukin-17F antibody
      • ML 1 antibody
      • ML1 antibody
      • Mutant IL 17F antibody
      • OTTHUMP00000016602 antibody
      see all

    画像

    • All lanes : Anti-IL17F antibody [H17F10A7] (ab90878) at 2 µg/ml

      Lane 1 : IL17 producing cells treated with Brefeldin A for 16 hours
      Lane 2 : IL17 producing cells treated with PMA and Ionomycin in the presence of Brefeldin A for 16 hours

      Secondary
      anti-mouse HRP conjugated polyclonal antibody.

      Performed under reducing conditions.

      Predicted band size : 18 kDa

    プロトコール

    参考文献

    ab90878 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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