Anti-IL17B Receptor 抗体 [RM0105-9J28] (ab86488)

製品の概要

  • 製品名Anti-IL17B Receptor antibody [RM0105-9J28]
    IL17B Receptor 一次抗体 製品一覧
  • 製品の詳細
    Rat monoclonal [RM0105-9J28] to IL17B Receptor
  • 特異性This antibody detects mouse IL17B Receptor in Western blotting, but not mouse IL17A receptor
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Mouse
  • 免疫原

    Mouse recombinant protein of the extracellular domain of IL17B Receptor

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab86488 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/1000. Predicted molecular weight: 56 kDa.

ターゲット情報

  • 関連性Recently, a number of cytokines belonging to the interleukin IL17 family have been identified. These are termed as IL17B, IL17C and IL17E. IL17 is a potent proinflammatory cytokine that plays roles in a number of diseases including rheumatoid arthritis, multiple sclerosis, and promotion of tumor growth. IL17B, C, and E like IL17 are able to induce proinflammatory responses. However, they do not bind to the IL17 receptor suggesting that additional IL17R related receptor might exist. Receptor for IL17B and IL17E have been independently isolated and have been designated as EV127 (in mouse) and IL17RH1 (in human), respectively. IL17E induces activation of NFkB pathway and like IL17 also induces production of IL8. IL17RH1 mRNA is highly expressed in Kidney and liver and at moderate level in small intestine, colon, and brain.
  • 細胞内局在Type I membrane protein (isoform 1). Secreted (isoform 2).
  • 参照データベース
  • 別名
    • CRL 4 antibody
    • CRL4 antibody
    • Cytokine receptor CRL4 antibody
    • EVI 27 antibody
    • EVI27 antibody
    • IL 17 receptor B antibody
    • IL 17 receptor homolog 1 antibody
    • IL 17B receptor antibody
    • IL 17RB antibody
    • IL 17Rh1 antibody
    • IL17BR antibody
    • IL17RB antibody
    • IL17RH1 antibody
    • Interleukin 17 receptor B antibody
    • Interleukin 17 receptor homolog 1 antibody
    • Interleukin 17 receptor homolog antibody
    • Interleukin 17B receptor antibody
    • MGC5245 antibody
    see all

Anti-IL17B Receptor antibody [RM0105-9J28] (ab86488) 使用論文

ab86488 has not yet been referenced specifically in any publications.

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The subisotype ofab86488 is IgG2a. Thus, the recommended isotype control to be used in flow cytometry would be ab18450.

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Flow cytometry has not yet been tested with this antibody. Therefore, we do not have data to show if and how well it would work in this application. But for UNTESTED species and/or applications, we have establish...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"