製品の概要

  • 製品名
    Anti-IL17A Receptor antibody [RM0104-10B27]
    IL17A Receptor 一次抗体 製品一覧
  • 製品の詳細
    Rat monoclonal [RM0104-10B27] to IL17A Receptor
  • 特異性
    This antibody detects mouse IL17A Receptor in Western blotting, but not IL17B Receptor.
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Mouse
  • 免疫原

    Mouse recombinant protein of the extracellular domain of IL17A Receptor

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • バッファー
    Preservative: None
    Constituents: PBS
  • Concentration information loading...
  • 精製度
    Protein A purified
  • 特記事項(精製)
    The IgG fraction of culture supernatant was purified by Protein A affinity chromatography.
  • ポリ/モノ
    モノクローナル
  • クローン名
    RM0104-10B27
  • アイソタイプ
    IgG2
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab86487 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/1000. Predicted molecular weight: 96 kDa.

ターゲット情報

  • 機能
    Receptor for IL17A and IL17F. Binds its IL17A ligand with low affinity, suggesting that additional components are involved in IL17A-induced signaling.
  • 組織特異性
    Widely expressed.
  • 関連疾患
    Defects in IL17RA are the cause of familial candidiasis type 5 (CANDF5) [MIM:613953]. CANDF5 is a rare disorder with altered immune responses and impaired clearance of fungal infections, selective against Candida. It is characterized by persistent and/or recurrent infections of the skin, nails and mucous membranes caused by organisms of the genus Candida, mainly Candida albicans.
  • 配列類似性
    Contains 1 SEFIR domain.
  • 翻訳後修飾
    Glycosylated.
  • 細胞内局在
    Membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CANDF5 antibody
    • CD217 antibody
    • CD217 antigen antibody
    • CDw217 antibody
    • CTLA8 antibody
    • HIL 17R antibody
    • hIL17R antibody
    • I17RA_HUMAN antibody
    • IL 17 receptor A antibody
    • IL 17 receptor antibody
    • IL 17RA antibody
    • IL-17 receptor A antibody
    • IL-17RA antibody
    • IL17 antibody
    • IL17A receptor antibody
    • IL17R antibody
    • IL17RA antibody
    • IMD51 antibody
    • Interleukin 17 receptor A antibody
    • Interleukin-17 receptor A antibody
    • MGC10262 antibody
    see all

プロトコール

参考文献

This product has been referenced in:
  • Deguise MO  et al. Differential induction of muscle atrophy pathways in two mouse models of spinal muscular atrophy. Sci Rep 6:28846 (2016). WB . Read more (PubMed: 27349908) »

See 1 Publication for this product

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