Anti-IL17A Receptor 抗体 [MM0371-8D15] (ab92608)

製品の概要

  • 製品名Anti-IL17A Receptor antibody [MM0371-8D15]
    IL17A Receptor 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [MM0371-8D15] to IL17A Receptor
  • アプリケーション適用あり: WB, Neutralisingmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant fragment, corresponding to the extracellular domain of Human IL17A Receptor.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファーPreservative: None
    Constituents: PBS
  • Concentration information loading...
  • 精製度Protein G purified
  • 特記事項(精製)Purified from tissue culture supernatant and 0.2 µm filtered.
  • ポリ/モノモノクローナル
  • クローン名MM0371-8D15
  • アイソタイプIgG1
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab92608 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
Neutralising
  • 追加情報Neut: Use at an assay dependent dilution.
    WB: 1/500 - 1/1000. Predicted molecular weight: 96 kDa.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Receptor for IL17A and IL17F. Binds its IL17A ligand with low affinity, suggesting that additional components are involved in IL17A-induced signaling.
    • 組織特異性Widely expressed.
    • 関連疾患Defects in IL17RA are the cause of familial candidiasis type 5 (CANDF5) [MIM:613953]. CANDF5 is a rare disorder with altered immune responses and impaired clearance of fungal infections, selective against Candida. It is characterized by persistent and/or recurrent infections of the skin, nails and mucous membranes caused by organisms of the genus Candida, mainly Candida albicans.
    • 配列類似性Contains 1 SEFIR domain.
    • 翻訳後修飾Glycosylated.
    • 細胞内局在Membrane.
    • Information by UniProt
    • 参照データベース
    • 別名
      • CANDF5 antibody
      • CD217 antibody
      • CD217 antigen antibody
      • CDw217 antibody
      • CTLA8 antibody
      • HIL 17R antibody
      • I17RA_HUMAN antibody
      • IL 17 receptor A antibody
      • IL 17 receptor antibody
      • IL 17RA antibody
      • IL-17 receptor A antibody
      • IL-17RA antibody
      • IL17 antibody
      • IL17A receptor antibody
      • IL17R antibody
      • IL17RA antibody
      • Interleukin 17 receptor A antibody
      • Interleukin-17 receptor A antibody
      • MGC10262 antibody
      see all

    Anti-IL17A Receptor antibody [MM0371-8D15] (ab92608) 使用論文

    ab92608 has not yet been referenced specifically in any publications.

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    Thank you for your inquiry.

    The principle of the neutralization ability of ab92608 is the following:

    IL-17 can stimulate IL-6 secretion from human stromal cells in a dose dependent manner.



    ab92608 can attenuate ...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"