製品の概要

  • 製品名Anti-IL17 antibody [20B4]
    IL17 一次抗体 製品一覧
  • 製品の詳細
    Rat monoclonal [20B4] to IL17
  • アプリケーション適用あり: WB, IP, ELISA, Flow Cytmore details
  • 種交差性
    交差種: Mouse
  • 免疫原

    Recombinant full length Mouse IL17.

製品の特性

  • 製品の状態Liquid
  • 保存方法Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze / thaw cycles.
  • バッファーpH: 7.20
    Constituents: 0.27% Potassium phosphate, 0.88% Sodium chloride
  • Concentration information loading...
  • ポリ/モノモノクローナル
  • クローン名20B4
  • アイソタイプIgG2a
  • 軽鎖の種類kappa
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab123250 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use at an assay dependent concentration. Predicted molecular weight: 17 kDa.
IP Use at an assay dependent concentration.
ELISA Use at an assay dependent concentration.
Flow Cyt Use at an assay dependent concentration. ab18450-Rat monoclonal IgG2a, is suitable for use as an isotype control with this antibody.

ターゲット情報

  • 機能Ligand for IL17RA and IL17RC (PubMed:17911633). The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC (PubMed:18684971). Involved in inducing stromal cells to produce proinflammatory and hematopoietic cytokines (PubMed:8676080).
  • 組織特異性Restricted to activated memory T-cells.
  • 配列類似性Belongs to the IL-17 family.
  • 翻訳後修飾Found both in glycosylated and nonglycosylated forms.
  • 細胞内局在Secreted.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CTLA 8 antibody
    • CTLA-8 antibody
    • CTLA8 antibody
    • Cytotoxic T lymphocyte associated antigen 8 antibody
    • Cytotoxic T lymphocyte associated protein 8 antibody
    • Cytotoxic T lymphocyte associated serine esterase 8 antibody
    • Cytotoxic T-lymphocyte-associated antigen 8 antibody
    • IL 17A antibody
    • IL-17 antibody
    • IL-17A antibody
    • IL17 antibody
    • IL17_HUMAN antibody
    • Il17a antibody
    • Interleukin 17 (cytotoxic T lymphocyte associated serine esterase 8) antibody
    • Interleukin 17A antibody
    • Interleukin-17A antibody
    • Interleukin17 antibody
    • Interleukin17A antibody
    • OTTHUMP00000016597 antibody
    • OTTMUSP00000046003 antibody
    see all

Anti-IL17 antibody [20B4] 画像

  • Mouse splenocytes were cultured under Th17 polarizing conditions. They were then left unstimulated (A) or stimulated with PMA and ionomycin in the presence of a protein transport inhibitor (B) and stained for intracellular IL-17A (y axis) using anti-mouse IL-17A clone 20B4.

Anti-IL17 antibody [20B4] (ab123250) 使用論文

ab123250 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"