製品の概要

  • 製品名Anti-IL15RA antibody
    IL15RA 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal to IL15RA
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Recombinant Fragment
    交差が予測される動物種: Human
  • 免疫原

    Recombinant fragment: ITCPPPMSVE HADIWVKSYS LYSRERYICN SGFKRKAGTS SLTECVLNKA TNVAHWTTPS LKCIRDPALV HQRPAPPSTV TTAGVTPQPE SLSPSGKEPA , corresponding to amino acids 31-131 of Human IL15RA

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab55285 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
  • 追加情報WB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Receptor for interleukin-15. Expression of different isoforms may alter or interfere with signal transduction. Isoform 5, isoform 6, isoform 7 and isoform 8 do not bind IL15. Signal transduction involves STAT3, STAT5, STAT6, JAK2 (By similarity) and SYK.
    • 組織特異性Isoform 1, isoform 3, isoform 4, isoform 5, isoform 6, isoform 7, isoform 8 and isoform 9 are widely expressed. Expressed in fetal brain with higher expression in the hippocampus and cerebellum than in cortex and thalamus. Higher levels of soluble sIL-15RA form in comparison with membrane-bound forms is present in all brain structures.
    • 配列類似性Contains 1 Sushi (CCP/SCR) domain.
    • 翻訳後修飾A soluble form (sIL-15RA) arises from proteolytic shedding of the membrane-anchored receptor. The cleavage involves ADAM17/TACE (By similarity). It also binds IL-15 and thus interferes with IL-15 binding to the membrane receptor.
      Phosphorylated by activated SYK.
      N-glycosylated and O-glycosylated.
    • 細胞内局在Secreted > extracellular space; Membrane. Nucleus membrane. Mainly found associated with the nuclear membrane and Endoplasmic reticulum membrane. Golgi apparatus membrane. Cytoplasmic vesicle membrane. Membrane. Isoform 5, isoform 6, isoform 7 and isoform 8 are associated with endoplasmic reticulum, Golgi and cytoplasmic vesicles, but not with the nuclear membrane.
    • Information by UniProt
    • 参照データベース
    • 別名
      • AA690181 antibody
      • CD215 antibody
      • I15RA_HUMAN antibody
      • IL 15R alpha antibody
      • IL-15 receptor subunit alpha antibody
      • IL-15R-alpha antibody
      • IL-15RA antibody
      • Il15ra antibody
      • Interleukin 15 receptor alpha antibody
      • Interleukin 15 receptor subunit alpha antibody
      • MGC104179 antibody
      • sIL-15 receptor subunit alpha antibody
      • sIL-15R-alpha antibody
      • sIL-15RA antibody
      • Soluble interleukin 15 receptor subunit alpha antibody
      • Soluble interleukin-15 receptor subunit alpha antibody
      see all

    Anti-IL15RA antibody 画像

    • Western blot against tagged recombinant protein immunogen using ab55285 IL15RA antibody at 1ug/ml. Predicted band size of immunogen is 37 kDa.

      This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Anti-IL15RA antibody (ab55285) 使用論文

    ab55285 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab55285.
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