Anti-IL13 receptor alpha 1 抗体 [GM1E7] (ab39418)

製品の概要

  • 製品名Anti-IL13 receptor alpha 1 antibody [GM1E7]
    IL13 receptor alpha 1 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [GM1E7] to IL13 receptor alpha 1
  • 特異性The antibody recognises IL13 Receptor 1 alpha transiently expressed on the cell surface of transfected BOSC cells as well as the native protein on monocytes.
  • アプリケーション適用あり: Flow Cytmore details
  • 種交差性
    交差種: Human
  • 免疫原

    cDNA of human IL-13R alpha 1 chain extracellular domain

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab39418 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Flow Cyt
  • 追加情報Flow Cyt: Use 25µl of a 2.5 µg/ml concentration.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Binds with low affinity to interleukin-13 (IL13). Together with IL4RA can form a functional receptor for IL13. Also serves as an alternate accessory protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but cannot replace the function of IL2RG in allowing enhanced interleukin-2 (IL2) binding activity.
    • 組織特異性Ubiquitous. Highest levels in heart, liver, skeletal muscle and ovary; lowest levels in brain, lung and kidney. Also found in B-cells, T-cells and endothelial cells.
    • 配列類似性Belongs to the type I cytokine receptor family. Type 5 subfamily.
    • ドメインThe WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.
      The box 1 motif is required for JAK interaction and/or activation.
    • 細胞内局在Membrane.
    • Information by UniProt
    • 参照データベース
    • 別名
      • bB128O4.2.1 (interleukin 13 receptor, alpha 1) antibody
      • Cancer/testis antigen 19 antibody
      • CD213a1 antibody
      • CD213A1 Antigen antibody
      • CT 19 antibody
      • CT19 antibody
      • I13R1_HUMAN antibody
      • IL 13 receptor subunit alpha 1 antibody
      • IL 13R alpha 1 antibody
      • IL 13R subunit alpha 1 antibody
      • IL 13Ra antibody
      • IL 13RA1 antibody
      • IL-13 receptor subunit alpha-1 antibody
      • IL-13R subunit alpha-1 antibody
      • IL-13R-alpha-1 antibody
      • IL-13RA1 antibody
      • IL13 receptor alpha 1 chain antibody
      • IL13R antibody
      • IL13RA antibody
      • Il13ra1 antibody
      • Interleukin 13 receptor alpha 1 antibody
      • Interleukin 13 receptor alpha 1 chain antibody
      • interleukin 13 receptor subunit alpha 1 antibody
      • Interleukin-13 receptor subunit alpha-1 antibody
      • NR 4 antibody
      • NR4 antibody
      see all

    Anti-IL13 receptor alpha 1 antibody [GM1E7] 画像

    • Specificity testing of ab39418. BOSC cells were transiently transfected with an expression vector encoding either the extracellular domain of IL13Rα1 or an irrelevant protein. Expression of the constructs was tested with an anti-tag monoclonal antibody (B, green curves), an irrelevant monoclonal antibody served as negative control (bluecurves). For specificity testing (A), purified ab39418 was tested on both the IL13Rα1 (red curve) and the irrelevant protein trans-fectants (green curve). A posi-tive signal was obtained only with IL13Rα1 transfected cells.

    Anti-IL13 receptor alpha 1 antibody [GM1E7] (ab39418) 使用論文

    ab39418 has not yet been referenced specifically in any publications.

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