Anti-IL-11 抗体 (ab76589)
Key features and details
- Rabbit polyclonal to IL-11
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-IL-11 antibody
IL-11 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to IL-11 -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Human
交差が予測される動物種: Macaque monkey -
免疫原
Synthetic peptide corresponding to Human IL-11 aa 1-100 conjugated to keyhole limpet haemocyanin.
(Peptide available asab90835) -
ポジティブ・コントロール
- This antibody gave a positive signal in Human Plasma Total Protein.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
pH: 7.40
Preservative: 0.02% Sodium azide
Constituent: PBS
Batches of this product that have a concentration < 1mg/ml may have BSA added as a stabilising agent. If you would like information about the formulation of a specific lot, please contact our scientific support team who will be happy to help. -
Concentration information loading...
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精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab76589の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
Use a concentration of 1 µg/ml. Detects a band of approximately 27 kDa (predicted molecular weight: 21 kDa).
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特記事項 |
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WB
Use a concentration of 1 µg/ml. Detects a band of approximately 27 kDa (predicted molecular weight: 21 kDa). |
ターゲット情報
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機能
Directly stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production. -
配列類似性
Belongs to the IL-6 superfamily. -
細胞内局在
Secreted. - Information by UniProt
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参照データベース
- Entrez Gene: 3589 Human
- Omim: 147681 Human
- SwissProt: P20809 Human
- Unigene: 467304 Human
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別名
- Adipogenesis inhibitory factor antibody
- AGIF antibody
- IL 11 antibody
see all
画像
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Anti-IL-11 antibody (ab76589) at 1 µg/ml + Human Plasma Total Protein Lysate at 10 µg
Secondary
Goat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution
Developed using the ECL technique.
Performed under reducing conditions.
Predicted band size: 21 kDa
Observed band size: 27 kDa why is the actual band size different from the predicted?
Additional bands at: 105 kDa. We are unsure as to the identity of these extra bands.
Exposure time: 15 minutesThe 27 kDa band observed is comparable to the molecular weight seen with other commercially available antibodies to IL-11.
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Anti-IL-11 antibody (ab76589) at 1 µg/ml + Recombinant human IL-11 protein (ab73620) at 0.1 µg
Secondary
Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilution
Developed using the ECL technique.
Performed under reducing conditions.
Predicted band size: 21 kDa
Observed band size: 19 kDa why is the actual band size different from the predicted?
Exposure time: 30 seconds
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (4)
ab76589 は 4 報の論文で使用されています。
- Tian Y et al. Immunosuppressants Tacrolimus and Sirolimus revert the cardiac antifibrotic properties of p38-MAPK inhibition in 3D-multicellular human iPSC-heart organoids. Front Cell Dev Biol 10:1001453 (2022). PubMed: 36438566
- Wang Y et al. Differential expression profile analysis of lncRNA UCA1α regulated mRNAs in bladder cancer. J Cell Biochem 119:1841-1854 (2018). PubMed: 28815726
- Marthandan S et al. Similarities in Gene Expression Profiles during In Vitro Aging of Primary Human Embryonic Lung and Foreskin Fibroblasts. Biomed Res Int 2015:731938 (2015). WB . PubMed: 26339636
- Jiang Y et al. Downregulation of SPARC expression inhibits the invasion of human trophoblast cells in vitro. PLoS One 8:e69079 (2013). WB . PubMed: 23935929