機能Receptor for IL10; binds IL10 with a high affinity.
組織特異性Spleen, thymus, and PBMC. Weak expression in pancreas, skeletal muscle, brain, heart, and kidney. Placenta, lung, and liver showed intermediate levels. Monocytes, B-cells, large granular lymphocytes, and T-cells express high levels.
関連疾患Inflammatory bowel disease 28
配列類似性Belongs to the type II cytokine receptor family.