Anti-IL-10 抗体 [B-S10] - BSA and Azide free (ab47222)
Key features and details
- Mouse monoclonal [B-S10] to IL-10 - BSA and Azide free
- Suitable for: Functional Studies
- Reacts with: Human
- Isotype: IgG1
製品の概要
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製品名
Anti-IL-10 antibody [B-S10] - BSA and Azide free
IL-10 一次抗体 製品一覧 -
製品の詳細
Mouse monoclonal [B-S10] to IL-10 - BSA and Azide free -
由来種
Mouse -
特異性
This antibody recognizes both natural and recombinant IL-10.
Blocks IL-10 induced inhibition of IL-6 synthesis on LPS activated monocytes.
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アプリケーション
適用あり: Functional Studiesmore details -
種交差性
交差種: Human -
免疫原
Recombinant full length protein corresponding to Human IL-10.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
pH: 7.30
Constituent: 100% PBS
Sterile-filtered through 0.22 µm. Carrier and preservative free -
キャリア・フリー
はい -
Concentration information loading...
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精製度
Ion Exchange Chromatography -
特記事項(精製)
This antibody is sterile filtered through 0.22 µm and treated to remove endotoxins. It is carrier and preservative free. -
ポリ/モノ
モノクローナル -
クローン名
B-S10 -
ミエローマ
x63-Ag8.653 -
アイソタイプ
IgG1 -
軽鎖の種類
kappa -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab47222の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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Functional Studies |
Use at an assay dependent concentration.
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特記事項 |
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Functional Studies
Use at an assay dependent concentration. |
ターゲット情報
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機能
Inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and by helper T-cells. -
組織特異性
Produced by a variety of cell lines, including T-cells, macrophages, mast cells and other cell types. -
配列類似性
Belongs to the IL-10 family. -
細胞内局在
Secreted. - Information by UniProt
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参照データベース
- Entrez Gene: 3586 Human
- Omim: 124092 Human
- SwissProt: P22301 Human
- Unigene: 193717 Human
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別名
- CSIF antibody
- Cytokine synthesis inhibitory factor antibody
- GVHDS antibody
see all
画像
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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Datasheet download
参考文献 (1)
ab47222 は 1 報の論文で使用されています。
- Bernatowicz PL et al. Synergistic effect of Dermatophagoides pteronyssinus allergens and dexamethasone on the expression of CD163 by peripheral blood mononuclear cells. Immunobiology 224:497-501 (2019). PubMed: 31133346