製品の概要

  • 製品名Anti-IL1 Receptor I antibody
    IL1 Receptor I 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to IL1 Receptor I
  • アプリケーション適用あり: ICC/IF, WB, IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat
  • 免疫原

    Recombinant fragment, corresponding to amino acids 18-241 of Human IL1 Receptor I (BC067506).

  • ポジティブ・コントロール
    • Human fetal spleen lysate. HeLa cell lysate. Human fetal skin tissue.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab106278 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ICC/IF Use at an assay dependent concentration. PubMed: 24950657
WB 1/500 - 1/1000. Detects a band of approximately 75 kDa (predicted molecular weight: 65 kDa).
IHC-P 1/100 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

ターゲット情報

  • 機能Receptor for interleukin-1 alpha (IL-1A), beta (IL-1B), and interleukin-1 receptor antagonist protein (IL-1RA). Binding to the agonist leads to the activation of NF-kappa-B. Signaling involves formation of a ternary complex containing IL1RAP, TOLLIP, MYD88, and IRAK1 or IRAK2.
  • 配列類似性Belongs to the interleukin-1 receptor family.
    Contains 3 Ig-like C2-type (immunoglobulin-like) domains.
    Contains 1 TIR domain.
  • 細胞内局在Membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Antigen CD121a antibody
    • CD121 antigen-like family member A antibody
    • CD121a antibody
    • CD121a antigen antibody
    • D2S1473 antibody
    • IL 1 antibody
    • IL 1R 1 antibody
    • IL 1R alpha antibody
    • IL 1RT1 antibody
    • IL-1R-1 antibody
    • IL-1R-alpha antibody
    • IL-1RT-1 antibody
    • IL-1RT1 antibody
    • IL1 inhibitor antibody
    • IL1R antibody
    • IL1R1 antibody
    • IL1R1_HUMAN antibody
    • IL1RA antibody
    • IL1RN antibody
    • IL1RT1 antibody
    • Interleukin 1 receptor alpha type 1 antibody
    • Interleukin 1 receptor antagonist protein (IRAP) antibody
    • Interleukin 1 receptor type I antibody
    • Interleukin receptor 1 antibody
    • Interleukin-1 receptor alpha antibody
    • Interleukin-1 receptor type 1 antibody
    • Interleukin-1 receptor type I antibody
    • p80 antibody
    see all

Anti-IL1 Receptor I antibody 画像

  • All lanes : Anti-IL1 Receptor I antibody (ab106278) at 1/500 dilution

    Lane 1 : Human fetal spleen lysate
    Lane 2 : HeLa cell lysate


    Predicted band size : 65 kDa
  • ab106278 staining interleukin 1 receptor 1 antibody in foetal epithelial skin tissue by immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections). Antibody dilution 1/100.

Anti-IL1 Receptor I antibody (ab106278) 使用論文

This product has been referenced in:
  • Oh YS  et al. Effects of bilateral vasectomy on the interleukin 1 system in mouse epididymis. Am J Reprod Immunol N/A:N/A (2016). IHC ; Mouse . Read more (PubMed: 27476761) »
  • Ma L  et al. Interleukin-1 beta guides the migration of cortical neurons. J Neuroinflammation 11:114 (2014). WB, IHC-FoFr, ICC/IF ; Rat . Read more (PubMed: 24950657) »

See all 2 Publications for this product

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ab106278 : sodium citrate buffer (10 mM Sodium citrate, pH 6.0), boil for 15 minutes.

Abcam has not validated the combination of species/application used in this Abreview.
Application Immunohistochemistry (Frozen sections)
Sample Mouse Tissue sections (Colon, Dorsal Root Ganglia)
Specification Colon, Dorsal Root Ganglia
Fixative Paraformaldehyde
Permeabilization Yes - 0.2% Triton X-100
Blocking step Serum as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 25°C
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投稿 Oct 19 2011

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"