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ab9722 は 81 報の論文で使用されています。

  • Wu J  et al. Roles of programmed death protein 1/programmed death-ligand 1 in secondary brain injury after intracerebral hemorrhage in rats: selective modulation of microglia polarization to anti-inflammatory phenotype. J Neuroinflammation 14:36 (2017). WB ; Rat . PubMed: 28196545
  • Zhu Y  et al. Electro-acupuncture promotes the proliferation of neural stem cells and the survival of neurons by downregulating miR-449a in rat with spinal cord injury. EXCLI J 16:363-374 (2017). PubMed: 28507480
  • Li JJ  et al. Biliverdin administration ameliorates cerebral ischemia reperfusion injury in rats and is associated with proinflammatory factor downregulation. Exp Ther Med 14:671-679 (2017). PubMed: 28672984
  • Choe JY & Kim SK Melittin inhibits osteoclast formation through the downregulation of the RANKL-RANK signaling pathway and the inhibition of interleukin-1ß in murine macrophages. Int J Mol Med 39:539-548 (2017). PubMed: 28204822
  • Tufanli O  et al. Targeting IRE1 with small molecules counteracts progression of atherosclerosis. Proc Natl Acad Sci U S A 114:E1395-E1404 (2017). PubMed: 28137856
  • Coucha M  et al. High fat diet dysregulates microRNA-17-5p and triggers retinal inflammation: Role of endoplasmic-reticulum-stress. World J Diabetes 8:56-65 (2017). PubMed: 28265343
  • Zhang H  et al. AIM2 Inflammasome Is Critical for Influenza-Induced Lung Injury and Mortality. J Immunol 198:4383-4393 (2017). PubMed: 28424239
  • Bouvier DS  et al. High Resolution Dissection of Reactive Glial Nets in Alzheimer's Disease. Sci Rep 6:24544 (2016). PubMed: 27090093
  • Kim DK  et al. Chromatographically isolated CD63+CD81+ extracellular vesicles from mesenchymal stromal cells rescue cognitive impairments after TBI. Proc Natl Acad Sci U S A 113:170-5 (2016). PubMed: 26699510
  • Pai CH  et al. Lack of Thromboxane Synthase Prevents Hypertension and Fetal Growth Restriction after High Salt Treatment during Pregnancy. PLoS One 11:e0151617 (2016). IHC . PubMed: 26974824
  • Verma N  et al. Intraneuronal Amylin Deposition, Peroxidative Membrane Injury and Increased IL-1ß Synthesis in Brains of Alzheimer's Disease Patients with Type-2 Diabetes and in Diabetic HIP Rats. J Alzheimers Dis 53:259-72 (2016). PubMed: 27163815
  • Dai YB  et al. Ablation of Liver X receptors a and ß leads to spontaneous peripheral squamous cell lung cancer in mice. Proc Natl Acad Sci U S A 113:7614-9 (2016). PubMed: 27335465
  • Hu Z  et al. Knockout of Ccr2 alleviates photoreceptor cell death in rodent retina exposed to chronic blue light. Cell Death Dis 7:e2468 (2016). WB . PubMed: 27831552
  • Gao Y  et al. Hydrogen-Rich Saline Attenuates Cardiac and Hepatic Injury in Doxorubicin Rat Model by Inhibiting Inflammation and Apoptosis. Mediators Inflamm 2016:1320365 (2016). PubMed: 28104928
  • Lin CH  et al. Molecular Mechanisms Responsible for Neuron-Derived Conditioned Medium (NCM)-Mediated Protection of Ischemic Brain. PLoS One 11:e0146692 (2016). IHC . PubMed: 26745377
  • Wu Q  et al. miR-489 inhibits silica-induced pulmonary fibrosis by targeting MyD88 and Smad3 and is negatively regulated by lncRNA CHRF. Sci Rep 6:30921 (2016). WB ; Mouse . PubMed: 27506999
  • Jia Y  et al. Brazilin exerts protective effects against renal ischemia-reperfusion injury by inhibiting the NF-?B signaling pathway. Int J Mol Med 38:210-6 (2016). IHC-P ; Rat . PubMed: 27247107
  • Lee BC  et al. Deubiquitinase CYLD acts as a negative regulator for bacterium NTHi-induced inflammation by suppressing K63-linked ubiquitination of MyD88. Proc Natl Acad Sci U S A 113:E165-71 (2016). Mouse . PubMed: 26719415
  • Oh YS  et al. Effects of bilateral vasectomy on the interleukin 1 system in mouse epididymis. Am J Reprod Immunol N/A:N/A (2016). IHC ; Mouse . PubMed: 27476761
  • Zhang Y  et al. Pretreatment with a combination of ligustrazine and berberine improves cardiac function in rats with coronary microembolization. Acta Pharmacol Sin 37:463-72 (2016). WB ; Rat . PubMed: 26924290
  • Bryukhovetskiy I  et al. Cancer stem cells and microglia in the processes of glioblastoma multiforme invasive growth. Oncol Lett 12:1721-1728 (2016). Rat . PubMed: 27602106
  • Littlewood-Evans A  et al. GPR91 senses extracellular succinate released from inflammatory macrophages and exacerbates rheumatoid arthritis. J Exp Med 213:1655-62 (2016). PubMed: 27481132
  • Cao G  et al. Ruscogenin Attenuates Cerebral Ischemia-Induced Blood-Brain Barrier Dysfunction by Suppressing TXNIP/NLRP3 Inflammasome Activation and the MAPK Pathway. Int J Mol Sci 17:N/A (2016). WB ; Mouse . PubMed: 27589720
  • Yang N  et al. TNF-a receptor antagonist attenuates isoflurane-induced cognitive impairment in aged rats. Exp Ther Med 12:463-468 (2016). WB ; Rat . PubMed: 27347079
  • Wang J  et al. The Effect of Repeated Electroacupuncture Analgesia on Neurotrophic and Cytokine Factors in Neuropathic Pain Rats. Evid Based Complement Alternat Med 2016:8403064 (2016). ICC/IF . PubMed: 27800006
  • Ambite I  et al. Molecular Basis of Acute Cystitis Reveals Susceptibility Genes and Immunotherapeutic Targets. PLoS Pathog 12:e1005848 (2016). WB, IHC ; Human . PubMed: 27732661
  • Akinrinmade FJ  et al. Changes in serum cytokine levels, hepatic and intestinal morphology in aflatoxin B1-induced injury: modulatory roles of melatonin and flavonoid-rich fractions from Chromolena odorata. Mycotoxin Res 32:53-60 (2016). PubMed: 26798045
  • Lewis JB  et al. Up-Regulation of Claudin-6 in the Distal Lung Impacts Secondhand Smoke-Induced Inflammation. Int J Environ Res Public Health 13:N/A (2016). WB ; Mouse . PubMed: 27763528
  • Tyrtyshnaia AA  et al. Acute neuroinflammation provokes intracellular acidification in mouse hippocampus. J Neuroinflammation 13:283 (2016). IHC ; Mouse . PubMed: 27809864
  • Ravindran R  et al. The amino acid sensor GCN2 controls gut inflammation by inhibiting inflammasome activation. Nature 531:523-7 (2016). IHC-P ; Mouse . PubMed: 26982722
  • Dadsetan S  et al. Infliximab reduces peripheral inflammation, neuroinflammation, and extracellular GABA in the cerebellum and improves learning and motor coordination in rats with hepatic encephalopathy. J Neuroinflammation 13:245 (2016). IHC-P ; Rat . PubMed: 27623772
  • Shi X  et al. Therapeutic effects of paeonol on methyl-4-phenyl-1,2,3,6-tetrahydropyridine/probenecid-induced Parkinson's disease in mice. Mol Med Rep 14:2397-404 (2016). PubMed: 27484986
  • Waldhuber A  et al. Uropathogenic Escherichia coli strain CFT073 disrupts NLRP3 inflammasome activation. J Clin Invest 126:2425-36 (2016). PubMed: 27214553
  • Wang SL  et al. Herpes simplex virus-1 infection or Simian virus 40-mediated immortalization of corneal cells causes permanent translocation of NLRP3 to the nuclei. Int J Ophthalmol 8:46-51 (2015). WB . PubMed: 25709906
  • Wang XP  et al. Protection of Gastrointestinal Mucosa from Acute Heavy Alcohol Consumption: The Effect of Berberine and Its Correlation with TLR2, 4/IL1ß-TNFa Signaling. PLoS One 10:e0134044 (2015). PubMed: 26226164
  • Lean QY  et al. Orally Administered Enoxaparin Ameliorates Acute Colitis by Reducing Macrophage-Associated Inflammatory Responses. PLoS One 10:e0134259 (2015). IF ; Mouse . PubMed: 26218284
  • Hu SJ  et al. Upregulation of P2RX7 in Cx3cr1-Deficient Mononuclear Phagocytes Leads to Increased Interleukin-1ß Secretion and Photoreceptor Neurodegeneration. J Neurosci 35:6987-96 (2015). IHC ; Mouse . PubMed: 25948251
  • Cowardin CA  et al. Inflammasome activation contributes to interleukin-23 production in response to Clostridium difficile. MBio 6:N/A (2015). PubMed: 25626905
  • Moyon S  et al. Demyelination causes adult CNS progenitors to revert to an immature state and express immune cues that support their migration. J Neurosci 35:4-20 (2015). PubMed: 25568099
  • Chiba K  et al. Involvement of IL-1 in the Maintenance of Masseter Muscle Activity and Glucose Homeostasis. PLoS One 10:e0143635 (2015). IHC . PubMed: 26599867
  • Berjaoui S  et al. Complex Inflammation mRNA-Related Response in ALS Is Region Dependent. Neural Plast 2015:573784 (2015). IHC-P ; Human . PubMed: 26301107
  • Lu J  et al. Progesterone-induced activation of membrane-bound progesterone receptors in murine macrophage cells. J Endocrinol 224:183-94 (2015). PubMed: 25472814
  • Suzuki N  et al. Mutual reinforcement of inflammation and carcinogenesis by the Helicobacter pylori CagA oncoprotein. Sci Rep 5:10024 (2015). PubMed: 25944120
  • O'Callaghan P  et al. Microglial Heparan Sulfate Proteoglycans Facilitate the Cluster-of-Differentiation 14 (CD14)/Toll-like Receptor 4 (TLR4)-Dependent Inflammatory Response. J Biol Chem 290:14904-14 (2015). PubMed: 25869127
  • Zhang Y  et al. NLRP3 Inflammasome Mediates Chronic Mild Stress-Induced Depression in Mice via Neuroinflammation. Int J Neuropsychopharmacol 18:N/A (2015). WB . PubMed: 25603858
  • Traba J  et al. Fasting and refeeding differentially regulate NLRP3 inflammasome activation in human subjects. J Clin Invest 125:4592-600 (2015). PubMed: 26529255
  • Zhang D  et al. TGFß-activated Kinase 1 (TAK1) Inhibition by 5Z-7-Oxozeaenol Attenuates Early Brain Injury after Experimental Subarachnoid Hemorrhage. J Biol Chem 290:19900-9 (2015). PubMed: 26100626
  • Chen L  et al. Apelin activates the expression of inflammatory cytokines in microglial BV2 cells via PI-3K/Akt and MEK/Erk pathways. Sci China Life Sci 58:531-40 (2015). PubMed: 25951933
  • Nga VD  et al. Effects of polycaprolactone-based scaffolds on the blood-brain barrier and cerebral inflammation. Tissue Eng Part A 21:647-53 (2015). PubMed: 25335965
  • Wong J  et al. Production of IL-1ß by bone marrow-derived macrophages in response to chemotherapeutic drugs: synergistic effects of doxorubicin and vincristine. Cancer Biol Ther 15:1395-403 (2014). PubMed: 25046000
  • Bersani F  et al. Bioengineered implantable scaffolds as a tool to study stromal-derived factors in metastatic cancer models. Cancer Res 74:7229-38 (2014). PubMed: 25339351
  • Ishii T  et al. Genetically induced oxidative stress in mice causes thrombocytosis, splenomegaly and placental angiodysplasia that leads to recurrent abortion. Redox Biol 2:679-85 (2014). WB ; Mouse . PubMed: 24936442
  • Sui Y  et al. IKKß links vascular inflammation to obesity and atherosclerosis. J Exp Med 211:869-86 (2014). Mouse . PubMed: 24799533
  • Luo B  et al. NLRP3 Gene Silencing Ameliorates Diabetic Cardiomyopathy in a Type 2 Diabetes Rat Model. PLoS One 9:e104771 (2014). WB ; Rat . PubMed: 25136835
  • Place DE  et al. Caspase-1-independent interleukin-1ß is required for clearance of Bordetella pertussis infections and whole-cell vaccine-mediated immunity. PLoS One 9:e107188 (2014). WB ; Mouse . PubMed: 25198773
  • Yoshida T  et al. Afadin requirement for cytokine expressions in keratinocytes during chemically induced inflammation in mice. Genes Cells 19:842-52 (2014). IHC-P ; Mouse . PubMed: 25297509
  • Bedarida T  et al. High-protein-low-carbohydrate diet: deleterious metabolic and cardiovascular effects depend on age. Am J Physiol Heart Circ Physiol 307:H649-57 (2014). PubMed: 25015969
  • Bouwman LI  et al. Inflammasome activation by Campylobacter jejuni. J Immunol 193:4548-57 (2014). WB . PubMed: 25267974
  • Rocha SW  et al. Diethylcarbamazine reduces chronic inflammation and fibrosis in carbon tetrachloride- (CCl4-) induced liver injury in mice. Mediators Inflamm 2014:696383 (2014). IHC ; Mouse . PubMed: 25374445
  • Phillips KL  et al. Interleukin-1 receptor antagonist deficient mice provide insights into pathogenesis of human intervertebral disc degeneration. Ann Rheum Dis N/A:N/A (2013). IHC ; Mouse . PubMed: 23396662
  • Agrawal V  et al. Surfactant protein (SP)-A suppresses preterm delivery and inflammation via TLR2. PLoS One 8:e63990 (2013). ICC/IF ; Mouse . PubMed: 23700442
  • Huang H  et al. Histones activate the NLRP3 inflammasome in Kupffer cells during sterile inflammatory liver injury. J Immunol 191:2665-79 (2013). PubMed: 23904166
  • Brown GT  et al. Lipopolysaccharide stimulates platelets through an IL-1ß autocrine loop. J Immunol 191:5196-203 (2013). PubMed: 24081990
  • Sakai K  et al. Absence of CD14 delays progression of prion diseases accompanied by increased microglial activation. J Virol 87:13433-45 (2013). Mouse . PubMed: 24089559
  • Wong J  et al. Small molecule kinase inhibitors block the ZAK-dependent inflammatory effects of doxorubicin. Cancer Biol Ther 14:56-63 (2013). PubMed: 23114643
  • Mascanfroni ID  et al. IL-27 acts on DCs to suppress the T cell response and autoimmunity by inducing expression of the immunoregulatory molecule CD39. Nat Immunol 14:1054-63 (2013). WB ; Mouse . PubMed: 23995234
  • Nyström S  et al. TLR activation regulates damage-associated molecular pattern isoforms released during pyroptosis. EMBO J 32:86-99 (2013). PubMed: 23222484
  • Dixon LJ  et al. Caspase-1-mediated regulation of fibrogenesis in diet-induced steatohepatitis. Lab Invest 92:713-23 (2012). WB ; Mouse . PubMed: 22411067
  • Yan S  et al. Pretreatment of cisplatin in recipients attenuates post-transplantation pancreatitis in murine model. Int J Biol Sci 8:298-309 (2012). PubMed: 22355266
  • Harris J  et al. Autophagy controls IL-1beta secretion by targeting pro-IL-1beta for degradation. J Biol Chem 286:9587-97 (2011). WB, ICC/IF ; Mouse . PubMed: 21228274
  • Keestra AM  et al. Early MyD88-dependent induction of interleukin-17A expression during Salmonella colitis. Infect Immun 79:3131-40 (2011). PubMed: 21576324
  • Drummond HA  et al. Renal inflammation and elevated blood pressure in a mouse model of reduced {beta}-ENaC. Am J Physiol Renal Physiol 301:F443-9 (2011). WB ; Mouse . PubMed: 21543417
  • Balog T  et al. Endomorphin-suppressed nitric oxide release from mice peritoneal macrophages. Neuropeptides 44:25-9 (2010). WB ; Mouse . PubMed: 20004470
  • Sozen T  et al. Role of interleukin-1beta in early brain injury after subarachnoid hemorrhage in mice. Stroke 40:2519-25 (2009). WB ; Mouse . PubMed: 19461019
  • Manczak M  et al. Neutralization of granulocyte macrophage colony-stimulating factor decreases amyloid beta 1-42 and suppresses microglial activity in a transgenic mouse model of Alzheimer's disease. Hum Mol Genet 18:3876-93 (2009). IHC-Fr ; Mouse . PubMed: 19617638
  • Cortes-Canteli M  et al. CCAAT/enhancer binding protein {beta} deficiency provides cerebral protection following excitotoxic injury. J Cell Sci 121:1224-34 (2008). WB, ICC/IF ; Mouse . PubMed: 18388310
  • Schmidt J  et al. Interrelation of inflammation and APP in sIBM: IL-1 beta induces accumulation of beta-amyloid in skeletal muscle. Brain 131:1228-40 (2008). IHC-Fr ; Human . PubMed: 18420712
  • Master SS  et al. Mycobacterium tuberculosis prevents inflammasome activation. Cell Host Microbe 3:224-32 (2008). PubMed: 18407066
  • Kvale EO  et al. Plasmacytoid DCs regulate recall responses by rapid induction of IL-10 in memory T cells. Blood 109:3369-76 (2007). PubMed: 17158235
  • Shayakhmetov DM  et al. Interference with the IL-1-signaling pathway improves the toxicity profile of systemically applied adenovirus vectors. J Immunol 174:7310-9 (2005). PubMed: 15905578
  • Kinsella S  et al. Bid Promotes K63-Linked Polyubiquitination of Tumor Necrosis Factor Receptor Associated Factor 6 (TRAF6) and Sensitizes to Mutant SOD1-Induced Proinflammatory Signaling in Microglia. eNeuro 3:N/A (0). PubMed: 27257617

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