Anti-IkB beta (phospho T19) 抗体 (ab63510)

製品の概要

  • 製品名Anti-IkB beta (phospho T19) antibody
    IKB beta 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to IkB beta (phospho T19)
  • アプリケーション適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic phosphopeptide derived from human IkB beta around the phosphorylation site of threonine 19

  • 特記事項


    Detects IkB beta only when phosphorylated at threonine 19.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab63510 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/1000. Detects a band of approximately 38 kDa (predicted molecular weight: 38 kDa).
ELISA 1/5000.

ターゲット情報

  • 機能Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further NFKBIA-dependent inactivation. Association with inhibitor kappa B-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation.
  • 組織特異性Expressed in all tissues examined.
  • 配列類似性Belongs to the NF-kappa-B inhibitor family.
    Contains 6 ANK repeats.
  • 翻訳後修飾Phosphorylated by RPS6KA1; followed by degradation. Interaction with NKIRAS1 and NKIRAS2 probably prevents phosphorylation.
  • 細胞内局在Cytoplasm. Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • I kappa B beta antibody
    • I-kappa-B-beta antibody
    • IkappaBbeta antibody
    • IKB beta antibody
    • IkB-B antibody
    • IkB-beta antibody
    • IKBB antibody
    • IKBB_HUMAN antibody
    • IkBbeta antibody
    • NF kappa BIB antibody
    • NF-kappa-B inhibitor beta antibody
    • NF-kappa-BIB antibody
    • Nfkbib antibody
    • Thyroid receptor interacting protein 9 antibody
    • Thyroid receptor-interacting protein 9 antibody
    • TR interacting protein 9 antibody
    • TR-interacting protein 9 antibody
    • TRIP-9 antibody
    • TRIP9 antibody
    see all

Anti-IkB beta (phospho T19) antibody (ab63510) 使用論文

ab63510 has not yet been referenced specifically in any publications.

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Thank you for your inquiry.

I heard back from the lab that the immunogen specificity is for T19. Swiss Prot (http://www.uniprot.org/uniprot/Q15653#ref1) also mentions a sequence conflict, based on experimental info, that marks 19: S -> T (...

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