製品の概要

  • 製品名Anti-IKB beta antibody
    IKB beta 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to IKB beta
  • アプリケーション適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Cow, Dog
  • 免疫原

    Synthetic peptide (Human). More details of the immunogen for this antibody are not available.

  • ポジティブ・コントロール
    • Jurkat Cell Lysate

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab42507 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 0.5 µg/ml. Detects a band of approximately 33 kDa (predicted molecular weight: 38 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
ELISA 1/1.77778.

ターゲット情報

  • 機能Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further NFKBIA-dependent inactivation. Association with inhibitor kappa B-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation.
  • 組織特異性Expressed in all tissues examined.
  • 配列類似性Belongs to the NF-kappa-B inhibitor family.
    Contains 6 ANK repeats.
  • 翻訳後修飾Phosphorylated by RPS6KA1; followed by degradation. Interaction with NKIRAS1 and NKIRAS2 probably prevents phosphorylation.
  • 細胞内局在Cytoplasm. Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • I kappa B beta antibody
    • I-kappa-B-beta antibody
    • IkappaBbeta antibody
    • IKB beta antibody
    • IkB-B antibody
    • IkB-beta antibody
    • IKBB antibody
    • IKBB_HUMAN antibody
    • IkBbeta antibody
    • NF kappa BIB antibody
    • NF-kappa-B inhibitor beta antibody
    • NF-kappa-BIB antibody
    • Nfkbib antibody
    • Thyroid receptor interacting protein 9 antibody
    • Thyroid receptor-interacting protein 9 antibody
    • TR interacting protein 9 antibody
    • TR-interacting protein 9 antibody
    • TRIP-9 antibody
    • TRIP9 antibody
    see all

Anti-IKB beta antibody 画像

  • All lanes : Anti-IKB beta antibody (ab42507) at 0.5 µg/ml

    Lane 1 : Marker
    Lane 2 : Jurkat Cell Lysate

    Secondary
    HRP conjugated anti-Rabbit IgG diluted 1:50,000-100,000

    Predicted band size : 38 kDa

Anti-IKB beta antibody (ab42507) 使用論文

ab42507 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab42507.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"