製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to IKB beta
  • アプリケーション
    適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Cow, Dog
  • 免疫原

    Synthetic peptide (Human). More details of the immunogen for this antibody are not available.

  • ポジティブ・コントロール
    • Jurkat Cell Lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab42507 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 0.5 µg/ml. Detects a band of approximately 33 kDa (predicted molecular weight: 38 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
ELISA 1/1.77778.

ターゲット情報

  • 機能
    Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further NFKBIA-dependent inactivation. Association with inhibitor kappa B-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation.
  • 組織特異性
    Expressed in all tissues examined.
  • 配列類似性
    Belongs to the NF-kappa-B inhibitor family.
    Contains 6 ANK repeats.
  • 翻訳後修飾
    Phosphorylated by RPS6KA1; followed by degradation. Interaction with NKIRAS1 and NKIRAS2 probably prevents phosphorylation.
  • 細胞内局在
    Cytoplasm. Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • I kappa B beta antibody
    • I-kappa-B-beta antibody
    • IkappaBbeta antibody
    • IKB beta antibody
    • IkB-B antibody
    • IkB-beta antibody
    • IKBB antibody
    • IKBB_HUMAN antibody
    • IkBbeta antibody
    • NF kappa BIB antibody
    • NF-kappa-B inhibitor beta antibody
    • NF-kappa-BIB antibody
    • Nfkbib antibody
    • Thyroid receptor interacting protein 9 antibody
    • Thyroid receptor-interacting protein 9 antibody
    • TR interacting protein 9 antibody
    • TR-interacting protein 9 antibody
    • TRIP-9 antibody
    • TRIP9 antibody
    see all

Anti-IKB beta antibody 画像

  • All lanes : Anti-IKB beta antibody (ab42507) at 0.5 µg/ml

    Lane 1 : Marker
    Lane 2 : Jurkat Cell Lysate

    Secondary
    HRP conjugated anti-Rabbit IgG diluted 1:50,000-100,000

    Predicted band size : 38 kDa

プロトコール

Anti-IKB beta antibody (ab42507) 使用論文

ab42507 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab42507.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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