製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to IGLL1
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Mouse, Human
  • 免疫原

    Full length protein, corresponding to amino acids 1-213 of Human IGLL1 (NP_064455.1)

  • ポジティブ・コントロール
    • Human or Mouse spleen lysate. IGLL1 transfected 293T cell lysate.

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • バッファー
    Preservative: None
    Constituents: 1X PBS, pH 7.2
  • Concentration information loading...
  • 精製度
    Protein A purified
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab103156 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500. Predicted molecular weight: 23 kDa.

ターゲット情報

  • 機能
    Critical for B-cell development.
  • 組織特異性
    Expressed only in pre-B-cells and a special B-cell line (which is surface Ig negative).
  • 関連疾患
    Defects in IGLL1 are the cause of agammaglobulinemia type 2 (AGM2) [MIM:613500]. It is a primary immunodeficiency characterized by profoundly low or absent serum antibodies and low or absent circulating B cells due to an early block of B-cell development. Affected individuals develop severe infections in the first years of life.
  • 配列類似性
    Contains 1 Ig-like C1-type (immunoglobulin-like) domain.
  • 細胞内局在
    Secreted.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 14.1 antibody
    • AGM2 antibody
    • CD179 antigen-like family member B antibody
    • CD179b antibody
    • CD179b antigen antibody
    • Ig lambda 5 antibody
    • Ig lambda-5 antibody
    • IGL1 antibody
    • IGL5 antibody
    • IGLJ14.1 antibody
    • IGLL antibody
    • Igll1 antibody
    • IGLL1_HUMAN antibody
    • IGO antibody
    • IGVPB antibody
    • Immunoglobulin lambda like polypeptide 1 precursor antibody
    • Immunoglobulin lambda-like polypeptide 1 antibody
    • Immunoglobulin omega polypeptide antibody
    • Immunoglobulin omega polypeptide chain antibody
    • Immunoglobulin related protein 14.1 antibody
    • Immunoglobulin-related protein 14.1 antibody
    • Lambda5 antibody
    • Pre B lymphocyte specific protein 2 antibody
    • VPREB2 antibody
    see all

画像

  • Anti-IGLL1 antibody (ab103156) at 1/500 dilution + Mouse spleen lysate at 50 µg

    Predicted band size : 23 kDa
  • Anti-IGLL1 antibody (ab103156) at 1/500 dilution + Human spleen lysate at 50 µg

    Predicted band size : 23 kDa
  • All lanes : Anti-IGLL1 antibody (ab103156) at 1/500 dilution

    Lane 1 : 293T cell line lysate transfected by IGLL1
    Lane 2 : non transfected 293T cell line lysate

    Lysates/proteins at 25 µg per lane.


    Predicted band size : 23 kDa

プロトコール

参考文献

ab103156 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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