製品の概要

  • 製品名Anti-IgG2 antibody [52G1]
    IgG2 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [52G1] to IgG2
  • 特異性Specific to -2 epitope inside Fc fragment of human IgG2. Reacts with fc region. No cross-reaction with human IgG1, IgG3, IgG4, IgA, IgM and IgE.
  • アプリケーション適用あり: Sandwich ELISAmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Human IgG2 from myeloma patient serum.

  • エピトープnot mapped
  • ポジティブ・コントロール
    • recombinant protein (calbiochem)
  • 特記事項Concentration varies from lot to lot and can be provided on request.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファーPreservative: 0.1% Sodium Azide
    Constituents: PBS, pH 7.4
  • Concentration information loading...
  • 精製度Protein A purified
  • 特記事項(精製)Purity tested by electrophoresis.
  • ポリ/モノモノクローナル
  • クローン名52G1
  • ミエローマSp2/0
  • アイソタイプIgG2a
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab1933 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Sandwich ELISA
  • 追加情報sELISA: Use at an assay dependent dilution as capture antibody.
    Can be paired for ELISA with Mouse monoclonal [5A9] to Human IgG (HRP) (ab7499).

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 関連性There are four IgG subclasses (IgG1, 2, 3 and 4) in humans, named in order of their abundance in serum (IgG1 being the most abundant). IgG2 is the only IgG subclass which passes through the placenta at a level generally lower than that found in the mother. A deficiency of IgG2 indicates a poor antibody response to bacterial polysaccharides and can lead to increased susceptibility to infections caused by encapsulated bacteria.
    • 細胞内局在Secreted
    • 参照データベース
    • 別名
      • Ig gamma-2 chain C region antibody
      • IGHG2 antibody
      • immunoglobulin Gm2 antibody
      • immunoglobulin heavy constant gamma 2 (G2m marker) antibody
      • immunoglobulin heavy constant, gamma 2 antibody
      see all

    Anti-IgG2 antibody [52G1] (ab1933) 使用論文

    ab1933 has not yet been referenced specifically in any publications.

    Product Wall

    I have reviewed these products and have been in touch with the labs regarding reactivity with Rhesus as requested. We would not recommend any human IgG2 antibody which we know is directed to the hinge region, such as ab1935, against Rhesus as the homol...

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    I can confirm that we have tested the antibodies ab7499 (Mouse monoclonal [5A9] to Human IgG (HRP) and ab1933 (Mouse monoclonal [52G1] to Human IgG2 (ab1933) in Sandwich ELISA. This was using ab1933 as capture and HRP-conjugated ab7499 for detection...

    Read More

    The concentration of this lot is 10.7 mg/ml. My apologies for the delay.Good luck with your experiments.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"