Anti-IGFBP3 抗体 [RM0096-11B16] (ab86461)
Key features and details
- Rat monoclonal [RM0096-11B16] to IGFBP3
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG2
製品の概要
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製品名
Anti-IGFBP3 antibody [RM0096-11B16]
IGFBP3 一次抗体 製品一覧 -
製品の詳細
Rat monoclonal [RM0096-11B16] to IGFBP3 -
由来種
Rat -
特異性
No cross reactivity seen to other IGFBP proteins. -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Human -
免疫原
Mouse recombinant IGFBP3.
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特記事項
ab86461 was produced from a hybridoma (mouse myeloma fused with spleen cells from an immunized rat).
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
バッファー
Constituent: PBS -
Concentration information loading...
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精製度
Immunogen affinity purified -
特記事項(精製)
IgG fraction of culture supernatant purified by Protein A/G affinity chromatography and 0.2 µm filtered. -
一次抗体 備考
ab86461 was produced from a hybridoma (mouse myeloma fused with spleen cells from an immunized rat). -
ポリ/モノ
モノクローナル -
クローン名
RM0096-11B16 -
アイソタイプ
IgG2 -
研究分野
関連製品
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Compatible Secondaries
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab86461の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB | (1) |
1/500 - 1/1000. Use under non reducing condition. Predicted molecular weight: 32 kDa.
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特記事項 |
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WB
1/500 - 1/1000. Use under non reducing condition. Predicted molecular weight: 32 kDa. |
ターゲット情報
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機能
IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. -
組織特異性
Expressed by most tissues. Present in plasma. -
配列類似性
Contains 1 IGFBP N-terminal domain.
Contains 1 thyroglobulin type-1 domain. -
発生段階
IGFBP3 levels are higher during extrauterine life and peak during puberty. -
ドメイン
The thyroglobulin type-1 domain mediates interaction with HN. -
翻訳後修飾
Phosphorylation sites are present in the extracelllular medium. -
細胞内局在
Secreted. - Information by UniProt
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参照データベース
- Entrez Gene: 3486 Human
- Omim: 146732 Human
- SwissProt: P17936 Human
- Unigene: 450230 Human
- Unigene: 697535 Human
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別名
- Acid stable subunit of the 140 K IGF complex antibody
- Binding protein 29 antibody
- Binding protein 53 antibody
see all
画像
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Anti-IGFBP3 antibody [RM0096-11B16] (ab86461) + Lysates of human placenta tissue
Predicted band size: 32 kDa
Observed band size: 40 kDa why is the actual band size different from the predicted?
データシートおよび資料
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Datasheet download
参考文献 (0)
ab86461 は論文での使用が確認できていません。