Anti-IgE 抗体, prediluted (ab75673)
Key features and details
- Rabbit polyclonal to IgE, prediluted
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-IgE antibody, prediluted
IgE 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to IgE, prediluted -
由来種
Rabbit -
特異性
This antibody recognizes IgE, epsilon heavy chain of human immunoglobulins. It does not cross-react with alpha (IgA), gamma (IgG), mu (IgM), or delta (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. -
アプリケーション
適用あり: IHC-Pmore details -
種交差性
交差種: Human -
免疫原
Full length IgE isolated from a pool of normal human sera.
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ポジティブ・コントロール
- Human Tonsil tissue
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特記事項
This antibody is useful in the identification of leukemias, plasmacytomas and certain non-Hodgkin’s lymphomas.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C. -
バッファー
pH: 7.60
Preservative: 0.0975% Sodium azide
Constituent: 0.79% Tris HCl
Containing antibody stabilizer -
Concentration information loading...
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精製度
Protein A purified -
一次抗体 備考
This antibody is useful in the identification of leukemias, plasmacytomas and certain non-Hodgkin’s lymphomas. -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab75673の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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IHC-P | (1) |
1/1. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
Ready to use. |
特記事項 |
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IHC-P
1/1. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. Ready to use. |
ターゲット情報
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関連性
IgE is the class of antibodies produced in the lungs, skin, and mucous membranes. It may protect against parasite invasion, but it is a major factor in allergic reactions. The antigen-specific IgE interacts with mast cells and eosinophils, triggers the release of histamine, leukotrienes and other substances that lead to the itching, sneezing and congestion of allergies - and the life threatening respiratory distress of asthma and anaphylactic shock. -
細胞内局在
Cell Membrane -
参照データベース
- Entrez Gene: 3497 Human
- Omim: 147180 Human
- SwissProt: P01854 Human
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別名
- Igh2 antibody
- IGHE antibody
- IGHEP1 antibody
- Immunoglobulin heavy constant epsilon antibody
画像
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (7)
ab75673 は 7 報の論文で使用されています。
- Chen F et al. The clinical efficacy and safety of anti-IgE therapy in recessive dystrophic epidermolysis bullosa. Clin Genet 101:110-115 (2022). PubMed: 34494659
- Zhu WX et al. Primary Hyper-IgE-Related Salivary Gland Disease: A New Disease Entity. Laryngoscope 132:2132-2138 (2022). PubMed: 35199865
- Zhu WX et al. Eosinophilic Sialodochitis: A Type of Chronic Obstructive Sialadenitis Related to Allergy. Laryngoscope 131:E800-E806 (2021). PubMed: 32621541
- Turner SD et al. Cell of Origin and Immunologic Events in the Pathogenesis of Breast Implant-Associated Anaplastic Large-Cell Lymphoma. Am J Pathol 190:2-10 (2020). PubMed: 31610171
- Hoh RA et al. Origins and clonal convergence of gastrointestinal IgE+ B cells in human peanut allergy. Sci Immunol 5:N/A (2020). PubMed: 32139586
- Ningyan G et al. The role of macrophage migration inhibitory factor in mast cell-stimulated fibroblast proliferation and collagen production. PLoS One 10:e0122482 (2015). PubMed: 25826375
- Motegi S et al. Elevated serum levels of TARC/CCL17, Eotaxin-3/CCL26 and VEGF in a patient with Kimura's disease and prurigo-like eruption. Acta Derm Venereol 94:112-3 (2014). PubMed: 23756566