製品の概要

  • 製品名Anti-IgE antibody [4G7]
    IgE 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [4G7] to IgE
  • 特異性This antibody reacts with human IgE. Specificity was confirmed by ELISA
  • アプリケーション適用あり: ELISAmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Full length native protein (purified) corresponding to Human IgE.

  • 特記事項This antibody recognizes an epitope different from the one recognized by ab774 and ab775.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • バッファーPreservative: 15mM Sodium Azide
    Constituents: PBS, pH 7.4
  • Concentration information loading...
  • 精製度>95% by SDS-PAGE
  • 特記事項(精製)Purified from ascites by DEAE chromatography and precipitation methods.
  • ポリ/モノモノクローナル
  • クローン名4G7
  • ミエローマunknown
  • アイソタイプIgG
  • 軽鎖の種類unknown
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab773 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA
  • 追加情報ELISA: Use at an assay dependant dilution.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 関連性IgE is the class of antibodies produced in the lungs, skin, and mucous membranes. It may protect against parasite invasion, but it is a major factor in allergic reactions. The antigen-specific IgE interacts with mast cells and eosinophils, triggers the release of histamine, leukotrienes and other substances that lead to the itching, sneezing and congestion of allergies - and the life threatening respiratory distress of asthma and anaphylactic shock.
    • 細胞内局在Cell Membrane
    • 参照データベース
    • 別名
      • Igh2 antibody
      • IGHE antibody
      • IGHEP1 antibody
      • Immunoglobulin heavy constant epsilon antibody

    Anti-IgE antibody [4G7] (ab773) 使用論文

    This product has been referenced in:
    • Mueller GA  et al. Hydrogen exchange nuclear magnetic resonance spectroscopy mapping of antibody epitopes on the house dust mite allergen Der p 2. J Biol Chem 276:9359-65 (2001). Read more (PubMed: 11134039) »
    • Smith AM  et al. The molecular basis of antigenic cross-reactivity between the group 2 mite allergens. J Allergy Clin Immunol 107:977-84 (2001). Read more (PubMed: 11398074) »

    See all 2 Publications for this product

    Product Wall

    Detailed epitope mapping was not performed (only cross-blocking studies with the three mAb to human IgE). Conjugates with HRP will be available, most probably will appear in the catalogue on September/October 2002. The preliminary studies showed that H...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"