Anti-IgA 抗体 [IgA5-3B] (Biotin) (ab53270)

製品の概要

  • 製品名Anti-IgA antibody [IgA5-3B] (Biotin)
    IgA 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [IgA5-3B] to IgA (Biotin)
  • 標識Biotin
  • 特異性ab53270 recognises IgA. It does not cross-react with IgG or IgM; it has been shown to detect secreted IgA in cat saliva and rhesus monkey jejunal washes
  • アプリケーション適用あり: ELISAmore details
  • 種交差性
    交差種: Cat, Dog, Human, Rhesus monkey, Marmoset (common)
  • 免疫原

    Purified monkey IgA, from serum.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • バッファーPreservative: 0.05% Sodium Azide
    Constituents: PBS, pH 7.2
  • Concentration information loading...
  • 精製度Protein A purified
  • 特記事項(精製)ab53270 is prepared by affinity chromatography on Protein A from tissue culture supernatant.
  • ポリ/モノモノクローナル
  • クローン名IgA5-3B
  • アイソタイプIgG1
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab53270 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA
  • 追加情報ELISA: Use at an assay dependent dilution. 1 - 10 ug/ml is a good starting point for ELISA.



    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 関連性Human IgA (immunoglobulin A) is a glycosylated protein of 160 kDa and is produced as a monomer or as a J chain linked dimer. Monomeric IgA constitutes 5-15 % of the serum immunoglobulins whereas dimeric IgA is localized to mucosa surfaces such as saliva, gastrointestinal secretion, bronchial fluids and milk. Mucosal IgA plays a major role in host defence by neutralising infectious agents at mucosal surfaces. The production is usually local and antigen specific IgA producing B cells can be found in regions under the lamina propria where they mature into dimeric IgA producing plasma cells. IgA deficiency is the most common immunodeficiency that may affect both serum and mucosal produced IgA. OR: The secretory component is a component of immunoglobulin A (IgA) which consists of a portion of the polymeric immunoglobulin receptor. Polymeric IgA binds to the polymeric immunoglobulin receptor on the basolateral surface of epithelial cells and is taken up into the cell via transcytosis. The receptor-IgA complex passes through the cellular compartments before being secreted on the luminal surface of the epithelial cells, still attached to the receptor. Proteolysis of the receptor occurs and the dimeric IgA molecule, along with the secretory component, are free to diffuse throughout the lumen.
    • 細胞内局在Secreted
    • 参照データベース
    • 別名
      • Hepatocellular carcinoma-associated protein TB6 antibody
      • Ig alpha 1 chain C region antibody
      • Ig alpha 2 chain C region antibody
      • IGHA antibody
      • IGHA1 antibody
      • IGHA2 antibody
      • Immunoglobulin heavy constant alpha 1 antibody
      • Immunoglobulin heavy constant alpha 2 A2m marker antibody
      • Immunoglobulin heavy constant alpha 2 antibody
      • PIgR antibody
      • Poly-Ig receptor antibody
      • polymeric immunoglobulin receptor antibody
      • polymeric immunoglobulin receptor Secretory component antibody
      see all

    Anti-IgA antibody [IgA5-3B] (Biotin) (ab53270) 使用論文

    ab53270 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"