製品の概要

  • 製品名Anti-IFNAR2 antibody
    IFNAR2 一次抗体 製品一覧
  • 製品の詳細
    Chicken polyclonal to IFNAR2
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Purified IFNAR2 intra cellular domain recombinant protein (15KD) (Human)

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab51545 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
  • 追加情報WB: 1/500 - 1/5000. Predicted molecular weight: 58 kDa. This antibody was tested using a 15kDA human IFNAR2 recombinant fragment only.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Associates with IFNAR1 to form the type I interferon receptor. Receptor for interferons alpha and beta. Involved in IFN-mediated STAT1, STAT2 and STAT3 activation. Isoform 1 and isoform 2 are directly involved in signal transduction due to their association with the TYR kinase, JAK1. Isoform 3 is a potent inhibitor of type I IFN receptor activity.
    • 組織特異性Isoform 3 is detected in the urine (at protein level). Expressed in blood cells. Expressed in lymphoblastoid and fibrosarcoma cell lines.
    • 配列類似性Belongs to the type II cytokine receptor family.
    • 翻訳後修飾Phosphorylated on tyrosine residues upon interferon binding. Phosphorylation at Tyr-337 or Tyr-512 are sufficient to mediate interferon dependent activation of STAT1, STAT2 and STAT3 leading to antiproliferative effects on many different cell types.
      Glycosylated.
    • 細胞内局在Secreted and Membrane.
    • Information by UniProt
    • 参照データベース
    • 別名
      • Human interferon alpha/beta receptor antibody
      • IFN alpha REC antibody
      • IFN R antibody
      • IFN-a/ßR2 antibody
      • IFN-a/ßRß antibody
      • IFN-alpha binding protein antibody
      • IFN-alpha/beta receptor 2 antibody
      • IFN-R-2 antibody
      • IFNABR antibody
      • IFNAR2 antibody
      • IFNARB antibody
      • IFNR antibody
      • INAR2_HUMAN antibody
      • Interferon (alpha beta and omega) receptor 2 antibody
      • Interferon alpha binding protein antibody
      • Interferon alpha/beta receptor 2 antibody
      • Interferon alpha/beta receptor beta chain antibody
      • Type I interferon receptor 2 antibody
      • Type I interferon receptor antibody
      see all

    Anti-IFNAR2 antibody (ab51545) 使用論文

    This product has been referenced in:

    See 1 Publication for this product

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