製品の概要

  • 製品名Anti-IFNAR1 antibody
    IFNAR1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to IFNAR1
  • 特異性ab91466 recognises isoform 2
  • アプリケーション適用あり: ELISA, Sandwich ELISA, WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide selected from the center region of Human IFNAR1 conjugated to KLH (NP_000620.2).

  • ポジティブ・コントロール
    • K562 cell line lysates.
  • 特記事項

    This antibody was used as a capture antibody in sELISA and was paired with ab10739 as detection antibody. Abreview 24657.

     

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab91466 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA
Sandwich ELISA
WB
  • 追加情報ELISA: 1/1000.
    WB: 1/100 - 1/500. Predicted molecular weight: 50 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Associates with IFNAR2 to form the type I interferon receptor. Receptor for interferons alpha and beta. Binding to type I IFNs triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and IFNR alpha- and beta-subunits themselves.
    • 組織特異性IFN receptors are present in all tissues and even on the surface of most IFN-resistant cells. Isoform 1, isoform 2 and isoform 3 are expressed in the IFN-alpha sensitive myeloma cell line U266S. Isoform 2 and isoform 3 are expressed in the IFN-alpha resistant myeloma cell line U266R. Isoform 1 is not expressed in IFN-alpha resistant myeloma cell line U266R.
    • 配列類似性Belongs to the type II cytokine receptor family.
      Contains 3 fibronectin type-III domains.
    • 翻訳後修飾Phosphorylated on tyrosine residues by TYK2 tyrosine kinase.
    • 細胞内局在Membrane.
    • Information by UniProt
    • 参照データベース
    • 別名
      • Alpha type antiviral protein antibody
      • AVP antibody
      • Beta type antiviral protein antibody
      • CRF2-1 antibody
      • Cytokine receptor class-II member 1 antibody
      • Cytokine receptor family 2 member 1 antibody
      • IFN alpha REC antibody
      • IFN alpha receptor antibody
      • IFN alpha/beta Receptor alpha antibody
      • IFN beta receptor antibody
      • IFN-alpha/beta receptor 1 antibody
      • IFN-R-1 antibody
      • IFNAR antibody
      • Ifnar1 antibody
      • IFNBR antibody
      • IFRC antibody
      • INAR1_HUMAN antibody
      • Interferon (alpha beta and omega) receptor 1 antibody
      • Interferon alpha/beta receptor 1 antibody
      • Interferon alpha/beta receptor alpha chain antibody
      • Interferon beta receptor 1 antibody
      • Type I interferon receptor 1 antibody
      see all

    Anti-IFNAR1 antibody 画像

    • Anti-IFNAR1 antibody (ab91466) at 1/100 dilution + K562 cell line lysates at 35 µg

      Predicted band size : 50 kDa

    Anti-IFNAR1 antibody (ab91466) 使用論文

    ab91466 has not yet been referenced specifically in any publications.

    Product Wall

    Abreviews
    Abcam guarantees this product to work in the species/application used in this Abreview.
    Application ELISA
    Sample Human Recombinant protein (IFNAR1 Recombinant Protein and K562 cell lysates)
    Specification IFNAR1 Recombinant Protein and K562 cell lysates
    Blocking step BSA as blocking agent for 24 hour(s) and 0 minute(s) · Concentration: 0.05% · Temperature: 4°C
    Type Sandwich (Detection)
    Username

    Christopher Leung

    Verified customer

    投稿 Aug 12 2011

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"