Anti-IFITM1 抗体 (ab105465)

製品の概要

• 製品名
  Anti-IFITM1 antibody
  IFITM1 一次抗体 製品一覧
• 製品の詳細
  Rabbit polyclonal to IFITM1
• アプリケーション
  適用あり: WBmore details
• 種交差性
  交差種: Human
  交差が予測される動物種: Chimpanzee, Macaque monkey, Gorilla, Orangutan
• 免疫原

  Synthetic peptide conjugated to KLH derived from within residues 1 - 100 of Human IFITM1.

  Immunogen の所有権に関して

• ポジティブ･コントロール
  • This antibody gave a positive signal in K562 whole cell lysate.

製品の特性

• 製品の状態
  Liquid
• 保存方法
  Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
• バッファー
  pH: 7.40
  Preservative: 0.02% Sodium azide
  Constituent: PBS
  Note: Batches of this product that have a concentration < 1mg/ml may have BSA added as a stabilising agent. If you would like information about the formulation of a specific lot, please contact our scientific support team who will be happy to help.
• Concentration information loading...
• 精製度
  Immunogen affinity purified
• ポリ/モノ
  ポリクローナル
• アイソタイプ
  IgG
• 研究分野
  • Immunology
  • Innate Immunity
  • Cytokines
  • Interferons

  • Signal Transduction
  • Adapters
  • Transmembrane

  • Stem Cells
  • Signaling Pathways
  • Wnt
  • Surface Molecules

  • Stem Cells
  • Signaling Pathways
  • TGF beta
  • Interferon gamma

  • Cancer
  • Oncoproteins/suppressors
  • Tumor suppressors
  • p53 pathway

  • Cancer
  • Tumor biomarkers
  • Other

関連製品

• Compatible Secondaries
  • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
  • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)

アプリケーション

ターゲット情報

• 機能
  IFN-induced antiviral protein that mediate cellular innate immunity to at least three major human pathogens, namely influenza A H1N1 virus, West Nile virus, and dengue virus by inhibiting the early step(s) of replication. Plays a key role in the antiproliferative action of IFN-gamma either by inhibiting the ERK activition or by arresting cell growth in G1 phase in a p53-dependent manner. Implicated in the control of cell growth. Component of a multimeric complex involved in the transduction of antiproliferative and homotypic adhesion signals.
• 配列類似性
  Belongs to the CD225 family.
• 翻訳後修飾
  Palmitoylation on membrane-proximal cysteines controls clustering in membrane compartments and antiviral activity against influenza virus.
• 細胞内局在
  Cell membrane.

• Target information above from: UniProt accession P13164 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• 参照データベース
  • Entrez Gene: 8519 Human
  • Omim: 604456 Human
  • SwissProt: P13164 Human
  • Unigene: 458414 Human
• 別名
  • 9-27 antibody
  • CD 225 antibody
  • CD 225 antigen antibody

  • CD225 antibody
  • CD225 antigen antibody
  • Dispanin subfamily A member 2a antibody
  • DSPA2a antibody
  • IFI 17 antibody
  • IFI17 antibody
  • IFITM1 antibody
  • IFM1_HUMAN antibody
  • Interferon induced protein 17 antibody
  • interferon induced transmembrane protein 1 (9-27) antibody
  • Interferon induced transmembrane protein 1 antibody
  • Interferon inducible protein 9-27 antibody
  • Interferon-induced protein 17 antibody
  • Interferon-induced transmembrane protein 1 antibody
  • Interferon-inducible protein 9-27 antibody
  • Leu 13 antibody
  • Leu 13 antigen antibody
  • Leu-13 antigen antibody
  • LEU13 antibody

  see all

プロトコール

• Western blot protocols