製品の概要

  • 製品名Anti-IDN3 antibody
    IDN3 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal to IDN3
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant fragment, corresponding to amino acids 66-175 of Human IDN3

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファーPreservative: None
    PBS, pH 7.2
  • Concentration information loading...
  • 精製度Protein G purified
  • ポリ/モノモノクローナル
  • アイソタイプIgG2a
  • 軽鎖の種類kappa
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab57054 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
  • 追加情報WB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Probably plays a structural role in chromatin. Involved in sister chromatid cohesion, possibly by interacting with the cohesin complex.
    • 組織特異性Widely expressed. Highly expressed in heart, skeletal muscle, fetal and adult liver, fetal and adult kidney. Expressed at intermediates level in thymus, placenta, peripheral leukocyte and small intestine. Weakly or not expressed in brain, colon, spleen and lung.
    • 関連疾患Cornelia de Lange syndrome 1
    • 配列類似性Belongs to the SCC2/Nipped-B family.
      Contains 5 HEAT repeats.
    • 発生段階In embryos, it is expressed in developing limbs and later in cartilage primordia of the ulna and of various hand bones. Sites of craniofacial expression include the cartilage primordium of the basioccipital and basisphenoid skull bones and elsewhere in the head and face, including a region encompassing the mesenchyme adjacent to the cochlear canal. Also expressed in the spinal column, notochord and surface ectoderm sclerotome and what seem to be migrating myoblasts. Expressed in the developing heart in the atrial and ventricular myocardium and in the ventricular tubeculae but absent in the endocardial cushions. Also expressed in the developing esophagus, trachea and midgut loops, in the bronchi of the lung and in the tubules of the metanephros. Expression in organs and tissues not typically affected in CDL (e.g. the developing trachea, bronchi, esophagus, heart and kidney) may reflect a bias towards underreporting of more subtle aspects of the phenotype or problems that typically present later in life. Expressed in the mesenchyme surrounding the cochlear canal possibly reflecting the hearing impairment commonly found. Weakly or not expressed in embryonic brain.
    • ドメインContains one Pro-Xaa-Val-Xaa-Leu (PxVxL) motif, which is required for interaction with chromoshadow domains. This motif requires additional residues -7, -6, +4 and +5 of the central Val which contact the chromoshadow domain.
    • 細胞内局在Nucleus.
    • Information by UniProt
    • 参照データベース
    • 製品の状態There are 3 isoforms produced by alternative splicing. Isoform 1 also known as: A; IDN3-A. Isoform 2 also known as: B; IDN3-B.
    • 別名
      • CDLS antibody
      • Colon tumor susceptibility 2 antibody
      • Delangin antibody
      • DKFZp434L1319 antibody
      • FLJ11203 antibody
      • FLJ12597 antibody
      • FLJ13354 antibody
      • FLJ13648 antibody
      • FLJ44854 antibody
      • IDN 3 antibody
      • IDN 3 protein antibody
      • IDN 3 protein isoform A antibody
      • IDN 3 protein isoform B antibody
      • IDN 3B antibody
      • IDN3 B antibody
      • IDN3 protein antibody
      • IDN3 protein isoform A antibody
      • IDN3 protein isoform B antibody
      • IDN3B antibody
      • Mis 4 antibody
      • Mis4 antibody
      • Nipbl antibody
      • NIPBL_HUMAN antibody
      • Nipped B homolog (Drosophila) antibody
      • Nipped B homolog antibody
      • Nipped B like antibody
      • Nipped B like protein antibody
      • Nipped-B-like protein antibody
      • Scc 2 antibody
      • SCC 2 homolog antibody
      • Scc2 antibody
      • SCC2 homolog antibody
      • Sister chromatid cohesion protein Mis4 antibody
      see all

    Anti-IDN3 antibody 画像

    • Western blot against tagged recombinant protein immunogen using ab57054 IDN3 antibody at 1ug/ml. Predicted band size of immunogen is 35 kDa

    Anti-IDN3 antibody (ab57054) 使用論文

    ab57054 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab57054.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"