製品の概要

  • 製品名
  • 製品の詳細
    Goat polyclonal to IDH3B
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Mouse
    交差が予測される動物種: Rat, Cow, Dog, Human, Pig
  • 免疫原

    Synthetic peptide:

    C-TTDFIKSVIGHLQTK

    , corresponding to C terminal amino acids 369-383 of Human IDH3B (NP_008830.2; NP_777281.1).

  • ポジティブ・コントロール
    • Mouse fetal kidney lysate, Mouse fetal skeletal muscle lysate, NIH3T3 cell lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab121016 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 0.03 - 0.1 µg/ml. Predicted molecular weight: 42 kDa.

ターゲット情報

  • 関連疾患
    Defects in IDH3B are the cause of retinitis pigmentosa type 46 (RP46) [MIM:612572]. RP is a retinal dystrophy belonging to the group of pigmentary retinopathies. RP is characterized by retinal pigment deposits visible on fundus examination and primary loss of rod photoreceptor cells followed by secondary loss of cone photoreceptors. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well.
  • 配列類似性
    Belongs to the isocitrate and isopropylmalate dehydrogenases family.
  • 細胞内局在
    Mitochondrion.
  • Information by UniProt
  • 参照データベース
  • 別名
    • FLJ11043 antibody
    • H-IDHB antibody
    • Idh3B antibody
    • IDH3B_HUMAN antibody
    • Isocitrate dehydrogenase [NAD] subunit beta antibody
    • Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial antibody
    • isocitrate dehydrogenase 3, beta subunit antibody
    • Isocitric dehydrogenase antibody
    • Isocitric dehydrogenase subunit beta antibody
    • MGC903 antibody
    • mitochondrial antibody
    • NAD(+)-specific ICDH antibody
    • NAD(+)-specific ICDH subunit beta antibody
    • NAD+-specific isocitrate dehydrogenase b subunit antibody
    • NAD+-specific isocitrate dehydrogenase beta antibody
    • OTTHUMP00000030023 antibody
    • OTTHUMP00000030024 antibody
    • RP46 antibody
    see all

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プロトコール

参考文献

This product has been referenced in:
  • Abdel Malik R  et al. AMP-Activated Protein Kinase a2 in Neutrophils Regulates Vascular Repair via Hypoxia-Inducible Factor-1a and a Network of Proteins Affecting Metabolism and Apoptosis. Circ Res 120:99-109 (2017). WB ; Mouse . Read more (PubMed: 27777247) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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