Anti-Id1 抗体 [2456C1a] (ab66495)
Key features and details
- Mouse monoclonal [2456C1a] to Id1
- Suitable for: WB
- Reacts with: Recombinant fragment
- Isotype: IgG1
製品の概要
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製品名
Anti-Id1 antibody [2456C1a]
Id1 一次抗体 製品一覧 -
製品の詳細
Mouse monoclonal [2456C1a] to Id1 -
由来種
Mouse -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Recombinant fragment -
免疫原
Recombinant fragment corresponding to Human Id1 (internal sequence).
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C. -
バッファー
pH: 7.4
Preservative: 0.05% Sodium azide
Constituents: PBS, 1% BSA -
Concentration information loading...
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精製度
Protein G purified -
特記事項(精製)
This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG depleted (~95%) fetal bovine serum. -
ポリ/モノ
モノクローナル -
クローン名
2456C1a -
アイソタイプ
IgG1 -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab66495の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
Use at an assay dependent concentration. Predicted molecular weight: 16 kDa.
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特記事項 |
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WB
Use at an assay dependent concentration. Predicted molecular weight: 16 kDa. |
ターゲット情報
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機能
ID (inhibitor of DNA binding) HLH proteins lack a basic DNA-binding domain but are able to form heterodimers with other HLH proteins, thereby inhibiting DNA binding. -
配列類似性
Contains 1 basic helix-loop-helix (bHLH) domain. -
発生段階
Expression correlates with proliferation in some types of cells. -
細胞内局在
Cytoplasm. Nucleus. - Information by UniProt
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別名
- bHLHb24 antibody
- Class B basic helix-loop-helix protein 24 antibody
- dJ857M17.1.2 (inhibitor of DNA binding 1, dominant negative helix-loop-helix protein) antibody
see all
データシートおよび資料
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Datasheet download
参考文献 (4)
ab66495 は 4 報の論文で使用されています。
- He Y et al. A noncanonical AR addiction drives enzalutamide resistance in prostate cancer. Nat Commun 12:1521 (2021). PubMed: 33750801
- Ohara RA et al. Citrullinated Inhibitor of DNA Binding 1 Is a Novel Autoantigen in Rheumatoid Arthritis. Arthritis Rheumatol 71:1241-1251 (2019). PubMed: 30861322
- Hu XM et al. ID1 contributes to cell growth invasion and migration in salivary adenoid cystic carcinoma. Mol Med Rep N/A:N/A (2017). PubMed: 29039489
- Snyder AD et al. Expression pattern of id proteins in medulloblastoma. Pathol Oncol Res 19:437-46 (2013). PubMed: 23397264