Anti-ICOS 抗体 [7E.17G9] (ab95630)
Key features and details
- Rat monoclonal [7E.17G9] to ICOS
- Suitable for: Flow Cyt
- Reacts with: Mouse
- Isotype: IgG2b
製品の概要
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製品名
Anti-ICOS antibody [7E.17G9]
ICOS 一次抗体 製品一覧 -
製品の詳細
Rat monoclonal [7E.17G9] to ICOS -
由来種
Rat -
アプリケーション
適用あり: Flow Cytmore details -
種交差性
交差種: Mouse -
免疫原
Mouse ICOS cDNA and ICOS hexahistidine fusion protein.
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ポジティブ・コントロール
- Three day ConA activated BALB/c splenocytes or Mouse splenocyte suspensions
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
pH: 7.20
Preservative: 0.09% Sodium azide
Constituents: 0.87% Sodium chloride, PBS -
Concentration information loading...
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精製度
Protein G purified -
ポリ/モノ
モノクローナル -
クローン名
7E.17G9 -
アイソタイプ
IgG2b -
軽鎖の種類
kappa -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab95630の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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Flow Cyt |
Use 0.06-1µg for 105-8 cells.
A 100 µl volume is recommended for staining the cell sample.
ab18536 - Rat monoclonal IgG2b, is suitable for use as an isotype control with this antibody.
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特記事項 |
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Flow Cyt
Use 0.06-1µg for 105-8 cells. A 100 µl volume is recommended for staining the cell sample.
ab18536 - Rat monoclonal IgG2b, is suitable for use as an isotype control with this antibody.
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ターゲット情報
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機能
Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. Essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. Does not up-regulate the production of interleukin-2, but superinduces the synthesis of interleukin-10. Prevents the apoptosis of pre-activated T-cells. Plays a critical role in CD40-mediated class switching of immunoglobin isotypes. -
組織特異性
Activated T-cells. Highly expressed on tonsillar T-cells, which are closely associated with B-cells in the apical light zone of germinal centers, the site of terminal B-cell maturation. Expressed at lower levels in thymus, lung, lymph node and peripheral blood leukocytes. Expressed in the medulla of fetal and newborn thymus. -
関連疾患
Immunodeficiency, common variable, 1 -
配列類似性
Contains 1 Ig-like V-type (immunoglobulin-like) domain. -
翻訳後修飾
N-glycosylated. -
細胞内局在
Secreted and Cell membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 54167 Mouse
- SwissProt: Q9WVS0 Mouse
- Unigene: 42044 Mouse
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別名
- Activation inducible lymphocyte immunomediatory molecule antibody
- Activation-inducible lymphocyte immunomediatory molecule antibody
- AILIM antibody
see all
画像
データシートおよび資料
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Datasheet download
参考文献 (0)
ab95630 は論文での使用が確認できていません。