製品の概要

  • 製品名
    Anti-ICAM2 antibody [mIC2/4 (3C4)] (Biotin)
    ICAM2 一次抗体 製品一覧
  • 製品の詳細
    Rat monoclonal [mIC2/4 (3C4)] to ICAM2 (Biotin)
  • 標識
    Biotin
  • 特異性
    Murine CD102 is a glycosylated cell surface protein that is broadly expressed on most leucocytes and is constitutively expressed on endothelial cells. CD102 interacts with the CD11a/CD18 integrin LFA-1.
  • アプリケーション
    適用あり: Flow Cytmore details
  • 種交差性
    交差種: Mouse
  • 免疫原

    Tissue/ cell preparation. COS cells transfected with murine ICAM-2.

  • 特記事項


    Clone mIC2/4 is reported to inhibit interactions between CD102 and LFA1.

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • バッファー
    pH: 7.40
    Preservative: 0.09% Sodium azide
    Constituents: PBS, 1% BSA
  • Concentration information loading...
  • 精製度
    Protein G purified
  • 特記事項(精製)
    Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant.
  • 一次抗体 備考
    Clone mIC2/4 is reported to inhibit interactions between CD102 and LFA1.
  • ポリ/モノ
    モノクローナル
  • クローン名
    mIC2/4 (3C4)
  • ミエローマ
    P3x63-Ag8.653
  • アイソタイプ
    IgG2a
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab33703 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Flow Cyt 1/1 - 1/5.

Use 10µl of suggested working dilution to label 106 cells.





ab18445-Rat monoclonal IgG2a, is suitable for use as an isotype control with this antibody.

ターゲット情報

  • 関連性
    ICAM2 is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin like C2 type domains, and bind to the leukocyte adhesion LFA1 protein. This protein may play a role in lymphocyte recirculation by blocking LFA1 dependent cell adhesion. It mediates adhesive interactions important for antigen specific immune response, NK cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance.
  • 細胞内局在
    Membrane; Single-pass type I membrane protein
  • 参照データベース
  • 別名
    • CD102 antibody
    • CD102 antigen antibody
    • ICAM 2 antibody
    • Intercellular adhesion molecule 2 antibody
    • Ly60 antibody
    see all

プロトコール

参考文献

This product has been referenced in:
  • Soede RD  et al. LFA-1 to LFA-1 signals involve zeta-associated protein-70 (ZAP-70) tyrosine kinase: relevance for invasion and migration of a T cell hybridoma. J Immunol 163:4253-61 (1999). Read more (PubMed: 10510363) »
  • Xu H  et al. Characterization of murine intercellular adhesion molecule-2. J Immunol 156:4909-14 (1996). Read more (PubMed: 8648141) »

See all 2 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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