Anti-ICAM1 抗体 [YN1/1.7.4] (Phycoerythrin) (ab25553)

製品の概要

  • 製品名
    Anti-ICAM1 antibody [YN1/1.7.4] (Phycoerythrin)
    ICAM1 一次抗体 製品一覧
  • 製品の詳細
    Rat monoclonal [YN1/1.7.4] to ICAM1 (Phycoerythrin)
  • 標識
    Phycoerythrin. Ex: 488nm, Em: 575nm
  • アプリケーション
    適用あり: Flow Cyt, WB, IP, Blocking, IHC-Frmore details
  • 種交差性
    交差種: Mouse
  • 免疫原

    The details of the immunogen for this antibody are not available.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab25553 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Flow Cyt Use 0.2µg for 106 cells.
WB Use at an assay dependent dilution. Detects a band of approximately 95 kDa (predicted molecular weight: 85-110 kDa).
IP Use at an assay dependent dilution.
Blocking Use at an assay dependent dilution.
IHC-Fr Use at an assay dependent dilution.

ターゲット情報

  • 機能
    ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus.
  • 配列類似性
    Belongs to the immunoglobulin superfamily. ICAM family.
    Contains 5 Ig-like C2-type (immunoglobulin-like) domains.
  • 翻訳後修飾
    Monoubiquitinated, which is promoted by MARCH9 and leads to endocytosis.
  • 細胞内局在
    Membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Antigen identified by monoclonal antibody BB2 antibody
    • BB 2 antibody
    • BB2 antibody
    • CD 54 antibody
    • CD_antigen=CD54 antibody
    • CD54 antibody
    • Cell surface glycoprotein P3.58 antibody
    • Human rhinovirus receptor antibody
    • ICAM 1 antibody
    • ICAM-1 antibody
    • ICAM1 antibody
    • ICAM1_HUMAN antibody
    • intercellular adhesion molecule 1 (CD54), human rhinovirus receptor antibody
    • Intercellular adhesion molecule 1 antibody
    • Major group rhinovirus receptor antibody
    • MALA 2 antibody
    • MALA2 antibody
    • MyD 10 antibody
    • MyD10 antibody
    • P3.58 antibody
    • Surface antigen of activated B cells, BB2 antibody
    see all

Anti-ICAM1 antibody [YN1/1.7.4] (Phycoerythrin) 画像

  • Flow cytometric analysis of C57BL/6 mouse splenocytes labelling ICAM1 with ab25553 at 0.1 μg/106 cells and labelling CD49b with a Rat Anti-Mouse CD49b-FITC antibody.

Anti-ICAM1 antibody [YN1/1.7.4] (Phycoerythrin) (ab25553) 使用論文

This product has been referenced in:
  • Qin L  et al. The roles of CD11/CD18 and ICAM-1 in acute Pseudomonas aeruginosa-induced pneumonia in mice. J Immunol 157:5016-21 (1996). Read more (PubMed: 8943409) »
  • Welder CA  et al. Inhibition of cell adhesion by microspheres coated with recombinant soluble intercellular adhesion molecule-1. J Immunol 150:2203-10 (1993). Read more (PubMed: 8095510) »

See all 4 Publications for this product

Product Wall

Abcam guarantees this product to work in the species/application used in this Abreview.
Application
Flow Cytometry
Sample
Mouse Cell (lymph node)
Specification
lymph node
Preparation
Cell harvesting/tissue preparation method: digestion collagenase
Sample buffer: PBS/BSA 1%
Permeabilization
No
Gating Strategy
PI negative
Username

Dr. alexandre garin

Verified customer

投稿 Jul 29 2008

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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