製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to ICA1
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Zebrafish
  • 免疫原

    Synthetic peptide corresponding to a region within the N terminal amino acids 72-121 (DLSKAIVLYQ KRICFLSQEE NELGKFLRSQ GFQDKTRAGK MMQATGKALC) of Human ICA1 (NP_004959).

  • ポジティブ・コントロール
    • Hela cell lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab81500 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Detects a band of approximately 55 kDa (predicted molecular weight: 55 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能
    May play a role in neurotransmitter secretion.
  • 組織特異性
    Expressed abundantly in pancreas, heart and brain with low levels of expression in lung, kidney, liver and thyroid.
  • 配列類似性
    Contains 1 AH domain.
  • 細胞内局在
    Cytoplasm > cytosol. Golgi apparatus membrane. Cytoplasmic vesicle > secretory vesicle membrane. Cytoplasmic vesicle > secretory vesicle > synaptic vesicle membrane. Predominantly cytosolic. Also exists as a membrane-bound form which has been found associated with synaptic vesicles and also with the Golgi complex and immature secretory granules.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 69 kDa islet cell autoantigen antibody
    • Diabetes mellitus type I autoantigen antibody
    • ICA 1 antibody
    • Ica1 antibody
    • ICA69 antibody
    • ICA69_HUMAN antibody
    • ICAp69 antibody
    • Islet cell autoantigen 1 (69kD) antibody
    • Islet cell autoantigen 1 69kDa antibody
    • Islet cell autoantigen 1 antibody
    • Islet cell autoantigen 1 isoform antibody
    • Islet cell autoantigen p69 antibody
    • OTTHUMP00000200933 antibody
    • OTTHUMP00000200934 antibody
    • OTTHUMP00000200941 antibody
    • OTTHUMP00000200993 antibody
    • p69 antibody
    see all

画像

  • Anti-ICA1 antibody (ab81500) at 1 µg/ml + HeLa cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 55 kDa
    Observed band size : 55 kDa

プロトコール

参考文献

This product has been referenced in:
  • Matsunaga K  et al. Rab2a and Rab27a cooperatively regulate the transition from granule maturation to exocytosis through the dual effector Noc2. J Cell Sci 130:541-550 (2017). Read more (PubMed: 27927751) »

See 1 Publication for this product

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