製品の概要

  • 製品名
    IBMX
  • 製品の詳細
    Non-specific cAMP and cGMP inhibitor
  • 生理活性の詳細
    Non-specific cAMP and cGMP inhibitor
  • 精製度
    > 98%

製品の特性

  • 体系名
    1-Methyl-3-(2-methylpropyl)-7H-purine-2,6-dione
  • 分子量
    222.24
  • 構造式
    Chemical Structure
  • 分子式
    C10H14N4O2
  • CAS 番号
    28822-58-4
  • PubChem 登録番号
    3758
  • 保存方法
    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • 溶解性
    Soluble in DMSO to 75 mM and in ethanol to 50 mM
  • 使用に関する注意

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES 線形表記
    CC(C)CN1C2=C(C(=O)N(C1=O)C)NC=N2
  • 由来

    Synthetic

  • 研究分野

関連製品

画像

  • 1e7 3T3-L1 cells were treated for 15 minutes with 1 µM dexamethasone (ab120743) and 1 µg x mL-1 insulin (ab123768) with the addition of 50 µM forskolin (ab120058), 0.5 mM IBMX (ab120840) or 0.1 mM 8-CPT-cAMP (ab120424), extracted according to the protocol. Lysates were diluted 50-fold, and tested in duplicates (+/-SD).

参考文献

This product has been referenced in:
  • Levitan IB & Norman J Different effects of cAMP and cGMP derivatives on the activity of an identified neuron: biochemical and electrophysiological analysis. Brain Res 187:415-29 (1980). Read more (PubMed: 6154497) »

See 0 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"

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