製品の概要

  • 製品名
    Hydroxychloroquine sulfate
  • 製品の詳細
    Anti-inflammatory and antimalarial agent
  • 生理活性の詳細
    Anti-inflammatory, antimalarial and antirheumatic agent. Inhibits toll-like receptor 9 (IC50 = 80 nM). Active in vivo.
  • 精製度
    > 99%

製品の特性

参考文献

This product has been referenced in:
  • Franklin BS  et al. Therapeutical targeting of nucleic acid-sensing Toll-like receptors prevents experimental cerebral malaria. Proc Natl Acad Sci U S A 108:3689-94 (2011). Read more (PubMed: 21303985) »
  • Kuznik A  et al. Mechanism of endosomal TLR inhibition by antimalarial drugs and imidazoquinolines. J Immunol 186:4794-804 (2011). Read more (PubMed: 21398612) »
  • Noman MZ  et al. Blocking hypoxia-induced autophagy in tumors restores cytotoxic T-cell activity and promotes regression. Cancer Res 71:5976-86 (2011). Read more (PubMed: 21810913) »

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