製品の概要

製品の詳細

  • 由来
    Synthetic
  • アミノ酸配列
    • 生物種
      Human
    • 配列
      CSSPPSSEFMDVN
    • 領域
      909 to 921

特性

Our Abpromise guarantee covers the use of ab23087 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Blocking

  • 製品の状態
    Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

関連情報

  • 別名
    • Deubiquitinating enzyme 11
    • Ubiquitin carboxyl-terminal hydrolase 11
    • Ubiquitin carboxyl-terminal hydrolase X linked
    • ubiquitin specific peptidase 11
    • Ubiquitin specific protease 11
    • Ubiquitin thiolesterase 11
    • Ubiquitin-specific-processing protease 11
    • UBP11_HUMAN
    • UHX1
    • USP11
    see all
  • 機能
    Protease that can remove conjugated ubiquitin from target proteins and polyubiquitin chains. Inhibits the degradation of target proteins by the proteasome. Plays a role in the regulation of pathways leading to NF-kappa-B activation. Plays a role in the regulation of DNA repair after double-stranded DNA breaks.
  • 配列類似性
    Belongs to the peptidase C19 family.
    Contains 1 DUSP domain.
  • 細胞内局在
    Nucleus. Cytoplasm. Predominantly nuclear. Associates with chromatin.
  • Information by UniProt

参考文献

ab23087 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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