製品の概要

製品の詳細

  • 由来Synthetic
  • アミノ酸配列
    • 生物種Human
    • 配列C-EDLSFNTDENSGR
    • 領域952 to 964

関連製品

特性

Our Abpromise guarantee covers the use of ab23224 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Blocking - Blocking peptide for Anti-TRIM37 antibody (ab13619)

  • 製品の状態Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

関連情報

  • 別名
    • E3 ubiquitin protein ligase TRIM37
    • E3 ubiquitin-protein ligase TRIM37
    • KIAA0898
    • MUL
    • MUL protein
    • Mulibrey nanism gene
    • Mulibrey nanism protein
    • POB 1
    • POB1
    • RING B box coiled coil protein
    • TEF 3
    • TEF3
    • TRI37_HUMAN
    • TRIM 37
    • Trim37
    • Tripartite motif containing 37
    • Tripartite motif containing 37 protein
    • Tripartite motif containing protein 37
    • Tripartite motif-containing protein 37
    see all
  • 機能E3 ubiquitin-protein ligase.
  • 組織特異性Ubiquitous.
  • パスウェイProtein modification; protein ubiquitination.
  • 関連疾患Defects in TRIM37 are the cause of mulibrey nanism (MUL) [MIM:253250]; also known as muscle-liver-brain-eye nanism. MUL is an autosomal recessive disorder that involves several tissues of mesodermal origin, implying a defect in a highly pleiotropic gene. Characteristic features include severe growth failure of prenatal onset and constrictive pericardium with consequent hepatomegaly. In addition, muscle hypotonia, J-shaped sella turcica, yellowish dots in the ocular fundi, typical dysmorphic features and hypoplasia of various endocrine glands causing hormonal deficiency are common.
  • 配列類似性Belongs to the TRIM/RBCC family.
    Contains 1 B box-type zinc finger.
    Contains 1 MATH domain.
    Contains 1 RING-type zinc finger.
  • 翻訳後修飾Auto-ubiquitinated.
  • 細胞内局在Cytoplasm > perinuclear region. Peroxisome. Found in vesicles of the peroxisome. Aggregates as aggresomes, a perinuclear region where certain misfolded or aggregated proteins are sequestered for proteasomal degradation.
  • Information by UniProt

Human TRIM37 peptide (ab23224) 使用論文

ab23224 has not yet been referenced specifically in any publications.

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