製品の概要

製品の詳細

  • 由来
    Synthetic
  • アミノ酸配列
    • 生物種
      Human
    • 配列
      C-NKPNSGKNDDKGNK
    • 領域
      37 to 50

関連製品

特性

Our Abpromise guarantee covers the use of ab45838 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Blocking - Blocking peptide for Anti-TPH2 antibody (ab40846)

  • 製品の状態
    Liquid
  • 備考

    ab40846 Anti-TPH2 antibody is the corresponding antibody to this peptide.

  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.

関連情報

  • 別名
    • MGC138871
    • ADHD7
    • FLJ37295
    • MGC138872
    • Neuronal tryptophan hydroxylase
    • NTPH
    • TPH 2
    • Tph2
    • TPH2_HUMAN
    • Tryptophan 5-hydroxylase 2
    • Tryptophan 5-monooxygenase 2
    • Tryptophan hydroxylase 2
    see all
  • 組織特異性
    Brain specific.
  • パスウェイ
    Aromatic compound metabolism; serotonin biosynthesis; serotonin from L-tryptophan: step 1/2.
  • 関連疾患
    Genetic variation in TPH2 may influence susceptibility to major depressive disorder (MDD) [MIM:608516].
    Defects in TPH2 are the cause of susceptibility to attention deficit-hyperactivity disorder type 7 (ADHD7) [MIM:613003]. ADHD is a neurobehavioral developmental disorder and is primarily characterized by the co-existence of attentional problems and hyperactivity, with each behavior occurring infrequently alone. Note=Naturally occurring variants of TPH2 with impaired enzyme activity could cause deficiency of serotonin production and result in an increased risk of developing behavioral disorders.
  • 配列類似性
    Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.
    Contains 1 ACT domain.
  • Information by UniProt

参考文献

ab45838 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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