製品の概要

製品の詳細

  • 由来
    Synthetic

関連製品

特性

Our Abpromise guarantee covers the use of ab41475 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Blocking - Blocking peptide for Anti-TIA1 antibody - C-terminal (ab40693)

  • 製品の状態
    Liquid
  • 備考

    - First try to dissolve a small amount of peptide in either water or buffer. The more charged residues on a peptide, the more soluble it is in aqueous solutions.
    - If the peptide doesn’t dissolve try an organic solvent e.g. DMSO, then dilute using water or buffer.
    - Consider that any solvent used must be compatible with your assay. If a peptide does not dissolve and you need to recover it, lyophilise to remove the solvent.
    - Gentle warming and sonication can effectively aid peptide solubilisation. If the solution is cloudy or has gelled the peptide may be in suspension rather than solubilised.
    - Peptides containing cysteine are easily oxidised, so should be prepared in solution just prior to use.

  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Information available upon request.

関連情報

  • 別名
    • Cytotoxic granule associated RNA binding protein
    • Cytotoxic granule associated RNA binding protein 1
    • mTIA-1
    • Nucleolysin TIA 1 isoform p40
    • Nucleolysin TIA-1 isoform p40
    • Nucleolysin TIA1 isoform p40
    • p40 TIA 1
    • p40-TIA-1
    • p40-TIA-1 (containing p15-TIA-1)
    • RNA binding protein TIA 1
    • RNA binding protein TIA1
    • RNA-binding protein TIA-1
    • T-cell-restricted intracellular antigen-1
    • Tia
    • TIA 1
    • TIA 1 cytotoxic granule associated RNA binding protein
    • TIA-1
    • TIA1
    • TIA1 cytotoxic granule associated RNA binding protein
    • TIA1 cytotoxic granule associated RNA binding protein like 1
    • TIA1 protein
    • TIA1_HUMAN
    • TIAL1
    • TIAR
    • WDM
    see all
  • 機能
    Involved in alternative pre-RNA splicing and regulation of mRNA translation by binding to AU-rich elements (AREs) located in mRNA 3' untranslated regions (3' UTRs). Possesses nucleolytic activity against cytotoxic lymphocyte target cells. May be involved in apoptosis.
  • 配列類似性
    Contains 3 RRM (RNA recognition motif) domains.
  • 細胞内局在
    Cytoplasmic granule. Nucleus. Accumulates in cytoplasmic stress granules (SG) following cellular damage.
  • Information by UniProt

参考文献

ab41475 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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