製品の概要

製品の詳細

  • 由来Synthetic
  • アミノ酸配列
    • 生物種Human

関連製品

特性

Our Abpromise guarantee covers the use of ab39872 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Western blot

  • 製品の状態Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: 0.02% Sodium Azide
    Constituents: 0.1% BSA, PBS, pH 7.2

関連情報

  • 別名
    • Class I cytokine receptor
    • CRL1
    • Cytokine receptor-like 1
    • I27RA_HUMAN
    • IL-27 receptor subunit alpha
    • IL-27R subunit alpha
    • IL-27R-alpha
    • IL-27RA
    • IL27R
    • IL27R alpha
    • Il27ra
    • Interleukin 27 receptor
    • Interleukin 27 receptor alpha chain precursor
    • Interleukin-27 receptor subunit alpha
    • Protein CRL1
    • T cell cytokine receptor type 1
    • TCCR
    • Type 1 T cell cytokine receptor
    • Type I T-cell cytokine receptor
    • WSX-1
    • WSX1
    • ZcytoR1
    see all
  • 機能Receptor for IL27. Requires IL6ST/gp130 to mediate signal transduction in response to IL27. This signaling system acts through STAT3 and STAT1. Involved in the regulation of Th1-type immune responses. Also appears to be involved in innate defense mechanisms.
  • 組織特異性Highly expressed in lymphoid tissues such as spleen, lymph nodes and peripheral blood leukocytes. Weakly expressed in other tissues examined including heart, brain, fetal and adult lung, liver, skeletal muscle, kidney, pancreas, prostate, testis, ovary, small intestine, kidney and colon. In the lymphoid system, higher level expression in CD4+ T-cell subsets than in CD8+ T-cell subsets. Also weaker expression in CD19+ B-cells and monocytes.
  • 配列類似性Belongs to the type I cytokine receptor family. Type 2 subfamily.
    Contains 3 fibronectin type-III domains.
  • ドメインThe WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.
    The box 1 motif is required for JAK interaction and/or activation.
  • 細胞内局在Membrane.
  • Information by UniProt

Human TCCR peptide (ab39872) 使用論文

ab39872 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"