製品の概要

  • 製品名
    Human SORBS1 peptide

製品の詳細

  • 由来
    Synthetic
  • 由来
    CHO cells
  • アミノ酸配列
    • 生物種
      Human
    • 配列
      C-GTFPGNYVKPLYL

関連製品

特性

Our Abpromise guarantee covers the use of ab18388 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Blocking - Blocking peptide for Anti-SORBS1 antibody (ab4551)

  • 製品の状態
    Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

関連情報

  • 別名
    • c-Cbl-associated protein
    • CAP
    • CBL Associated Protein
    • Ponsin
    • SH3 domain protein 5
    • SH3D5
    • SH3P12
    • Sorbin and SH3 Domain Containing 1
    • Sorbin and SH3 domain-containing protein 1
    • Sorbs1
    • SRBS1_HUMAN
    see all
  • 機能
    Plays a role in tyrosine phosphorylation of CBL by linking CBL to the insulin receptor. Required for insulin-stimulated glucose transport. Involved in formation of actin stress fibers and focal adhesions.
  • 組織特異性
    Detected in skeletal muscle (at protein level). Widely expressed with highest levels in heart and skeletal muscle.
  • 配列類似性
    Contains 3 SH3 domains.
    Contains 1 SoHo domain.
  • 翻訳後修飾
    O-glycosylated.
  • 細胞内局在
    Cell junction > adherens junction. Cell membrane. Cytoplasm > cytoskeleton. Cell junction > focal adhesion. Colocalizes with actin stress fibers. Also detected at the plasma membrane and in neuronal intranuclear inclusions. Colocalized with PXN at focal adhesions during myogenic differentiation.
  • Information by UniProt

参考文献

ab18388 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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