The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Blocking - Blocking peptide for Anti-SNX16 antibody (ab4151)
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Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
May be involved in several stages of intracellular trafficking. Plays a role in protein transport from early to late endosomes. Plays a role in protein transport to the lysosome. Promotes degradation of EGFR after EGF signaling. Plays a role in intracellular transport of vesicular stomatitis virus nucleocapsids from the endosome to the cytoplasm.
Detected in placenta, lung, liver,heart and pancreas.
Belongs to the sorting nexin family. Contains 1 PX (phox homology) domain.
The PX domain mediates interaction with membranes enriched in phosphatidylinositol 3-phosphate.
Early endosome membrane. Late endosome membrane. Cytoplasm. Lysosome.