製品の概要

製品の詳細

  • 由来
    Synthetic
  • アミノ酸配列
    • 生物種
      Human
    • 配列
      C-HSEPLMPHNATYPD
    • 領域
      166 to 179

関連製品

特性

Our Abpromise guarantee covers the use of ab48057 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Blocking - Blocking peptide for Anti-SMAD9 antibody (ab48011)

  • 製品の状態
    Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

関連情報

  • 別名
    • MAD homolog 9
    • Madh6
    • Mothers against decapentaplegic
    • Mothers against decapentaplegic homolog 9
    • Mothers against DPP homolog 9
    • SMAD 9
    • SMAD family member 9
    • SMAD, mothers against DPP homolog 9 (Drosophila)
    • SMAD8A
    • SMAD8B
    • Smad9
    • SMAD9_HUMAN
    see all
  • 機能
    Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD9 is a receptor-regulated SMAD (R-SMAD).
  • 組織特異性
    Expressed in heart, brain, placenta, lung, skeletal muscle, prostate, testis, ovary and small intestine. Also expressed in fetal brain, lung and kidney.
  • 関連疾患
    Pulmonary hypertension, primary, 2
  • 配列類似性
    Belongs to the dwarfin/SMAD family.
    Contains 1 MH1 (MAD homology 1) domain.
    Contains 1 MH2 (MAD homology 2) domain.
  • 翻訳後修飾
    Phosphorylated on serine by BMP (bone morphogenetic proteins) type 1 receptor kinase.
  • 細胞内局在
    Cytoplasm. Nucleus. In the cytoplasm in the absence of ligand. Migration to the nucleus when complexed with SMAD4.
  • Information by UniProt

参考文献

ab48057 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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