製品の概要

製品の詳細

  • 由来Synthetic

関連製品

特性

Our Abpromise guarantee covers the use of ab97416 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Blocking - Blocking peptide for Anti-SLC40A1 antibody (ab85370)

  • 精製度70 - 90% by HPLC.

  • 製品の状態Liquid
  • 備考

    - First try to dissolve a small amount of peptide in either water or buffer. The more charged residues on a peptide, the more soluble it is in aqueous solutions.
    - If the peptide doesn’t dissolve try an organic solvent e.g. DMSO, then dilute using water or buffer.
    - Consider that any solvent used must be compatible with your assay. If a peptide does not dissolve and you need to recover it, lyophilise to remove the solvent.
    - Gentle warming and sonication can effectively aid peptide solubilisation. If the solution is cloudy or has gelled the peptide may be in suspension rather than solubilised.
    - Peptides containing cysteine are easily oxidised, so should be prepared in solution just prior to use.

  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Information available upon request.

関連情報

  • 別名
    • Ferroportin
    • Ferroportin 1
    • Ferroportin-1
    • FPN1
    • HFE4
    • IREG1
    • iron regulated gene 1
    • Iron regulated transporter 1
    • Iron-regulated transporter 1
    • MST079
    • MSTP079
    • MTP1
    • putative ferroportin 1 variant IIIA
    • putative ferroportin 1 variant IIIB
    • S40A1_HUMAN
    • SLC11A3
    • SLC11A3, formerly
    • SLC40A1
    • solute carrier family 11 (proton-coupled divalent metal ion transporters), member 3
    • solute carrier family 11 (proton-coupled divalent metal ion transporters), member 3, formerly
    • solute carrier family 40 (iron-regulated transporter), member 1
    • Solute carrier family 40 member 1
    see all
  • 機能May be involved in iron export from duodenal epithelial cell and also in transfer of iron between maternal and fetal circulation. Mediates iron efflux in the presence of a ferroxidase (hephaestin and/or ceruloplasmin).
  • 組織特異性Expressed in placenta, intestine, muscle and spleen.
  • 関連疾患Defects in SLC40A1 are the cause of hemochromatosis type 4 (HFE4) [MIM:606069]. HFE4 is an autosomal dominant iron-loading disorder characterized by early iron accumulation in reticuloendothelial cells and a marked increase in serum ferritin before elevation of the transferrin saturation.
  • 配列類似性Belongs to the SLC40A transporter family.
  • 細胞内局在Cell membrane. Localized to the basolateral membrane of polarized epithelial cells.
  • Information by UniProt

Human SLC40A1 peptide (ab97416) 使用論文

ab97416 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your reply.

I am sorry that you are having issues with these antibodies in western blot. Having looked over all of the protocol information you sent previously and I cannot think of anything else that may prove useful. I was jus...

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Thank you for confirming these details and for your cooperation. The details provided enable us to closely monitor the quality of our products. I am sorry this product did not perform as stated on the datasheet and for the inconvenience this has cau...

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I am sorry to hear of the continued difficulties that you are experiencing.

The antibody is covered under our Abpromise for six months and is guaranteed to work in WB. IAs protocol tips and use of the blocking peptide did not yield satisfact...

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Thank you for confirming these details and for your cooperation. The details provided enable us to closely monitor the quality of our products. I am sorry this product did not perform as stated on the datasheet and for the inconvenience this has cau...

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Thank you for contacting us. We do not carry sample sizes. However if you would provide me with the Abcam order confirmation number for ab85370 I will send the peptide to you. I hope this information is helpful to you. Please do not hesitate to c...

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Thank you for that additional information. These additional detail are extremely helpful in understanding the problem.

I am sorry that you have been experiencing these issues with our product. I would however recommend using a peptide blocki...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"