製品の概要

製品の詳細

  • 由来Synthetic
  • アミノ酸配列
    • 生物種Human
    • 配列C-TKNLSEKRSAKII
    • 領域1192 to 1204

特性

Our Abpromise guarantee covers the use of ab23175 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Blocking

  • 製品の状態Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

関連情報

  • 別名
    • DKFZp667N084
    • DKFZp686I15116
    • KIA001LB
    • PDZ domain containing guanine nucleotide exchange factor (GEF) 2
    • PDZ domain containing guanine nucleotide exchange factor 2
    • PDZ domain containing guanine nucleotide exchange factor I
    • PDZ domain-containing guanine nucleotide exchange factor 2
    • PDZ GEF 2
    • PDZ GEF2
    • PDZ-GEF2
    • PDZGEF 2
    • PDZGEF2
    • RA GEF 2
    • RA GEF2
    • RA-GEF-2
    • RAGEF 2
    • Rap guanine nucleotide exchange factor (GEF) 6
    • Rap guanine nucleotide exchange factor 2
    • Rap guanine nucleotide exchange factor 6
    • RAPGEF6
    • RPGF6_HUMAN
    see all
  • 機能Guanine nucleotide exchange factor (GEF) for Rap1A, Rap2A and M-Ras GTPases. Does not interact with cAMP.
  • 組織特異性Isoform 3 has highest expression levels in the brain, heart, liver, lung and placenta and is barely detectable in skeletal muscle, kidney and pancreas.
  • 配列類似性Contains 1 cyclic nucleotide-binding domain.
    Contains 1 N-terminal Ras-GEF domain.
    Contains 1 PDZ (DHR) domain.
    Contains 1 Ras-associating domain.
    Contains 1 Ras-GEF domain.
  • 翻訳後修飾Phosphorylated upon DNA damage, probably by ATM or ATR.
  • 細胞内局在Cytoplasm. Cell membrane. Upon binding to M-Ras, it translocates to the plasma membrane.
  • Information by UniProt

Human RAGEF2 peptide (ab23175) 使用論文

ab23175 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab23175.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"