製品の概要

製品の詳細

  • 由来
    Synthetic
  • アミノ酸配列
    • 生物種
      Human
    • 配列
      GSKKLKRVGLSQE-C
    • 領域
      2 to 14

特性

Our Abpromise guarantee covers the use of ab22970 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Blocking

  • 製品の状態
    Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

関連情報

  • 別名
    • DNA repair protein RAD51 homolog 2
    • hREC2
    • MGC34245
    • OTTHUMP00000212251
    • OTTHUMP00000212253
    • OTTHUMP00000212254
    • OTTHUMP00000212255
    • R51H2
    • RA51B_HUMAN
    • RAD51 homolog B
    • RAD51 homolog B (S. cerevisiae)
    • RAD51 like 1
    • RAD51 like protein 1
    • RAD51-like protein 1
    • Rad51B
    • RAD51L1
    • REC2
    • RecA like protein
    • Recombination repair protein
    see all
  • 機能
    Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents. May promote the assembly of presynaptic RAD51 nucleoprotein filaments. The RAD51B-RAD51C dimer exhibits single-stranded DNA-dependent ATPase activity. The BCDX2 complex binds single-stranded DNA, single-stranded gaps in duplex DNA and specifically to nicks in duplex DNA.
  • 組織特異性
    Expressed in a wide range of tissues.
  • 関連疾患
    Note=A chromosomal aberration involving RAD51L1 is found in pulmonary chondroid hamartoma. Translocation t(6;14)(p21;q23-24) with HMGA1.
    Note=A chromosomal aberration involving RAD51L1 is found in uterine leiomyoma. Translocation t(12;14)(q15;q23-24) with HMGA2.
  • 配列類似性
    Belongs to the RecA family. RAD51 subfamily.
  • 細胞内局在
    Nucleus.
  • Information by UniProt

参考文献

ab22970 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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