製品の概要

製品の詳細

  • 由来Synthetic
  • アミノ酸配列
    • 生物種Human
    • 配列NRPAPVEVSYKHMR-C
    • 領域5 to 18

特性

Our Abpromise guarantee covers the use of ab22906 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Blocking

  • 製品の状態Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

関連情報

  • 別名
    • Potentially prenylated protein tyrosine phosphatase
    • PRL 3
    • PRL R
    • PRL-3
    • PRL-R
    • PRL3
    • PRLR
    • Protein tyrosine phosphatase 4a3
    • Protein tyrosine phosphatase type IVA 3
    • Protein-tyrosine phosphatase 4a3
    • Protein-tyrosine phosphatase of regenerating liver 3
    • PTP 4A3
    • PTP4A3
    • TP4A3_HUMAN
    see all
  • 機能Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. Enhances cell proliferation, cell motility and invasive activity, and promotes cancer metastasis. May be involved in the progression of cardiac hypertrophy by inhibiting intracellular calcium mobilization in response to angiotensin II.
  • 組織特異性Mainly expressed in cardiomyocytes and skeletal muscle; also found in pancreas. Consistently overexpressed in colon cancer metastasis.
  • 配列類似性Belongs to the protein-tyrosine phosphatase family.
    Contains 1 tyrosine-protein phosphatase domain.
  • 翻訳後修飾Farnesylated. Farnesylation is required for membrane targeting.
  • 細胞内局在Cell membrane. Early endosome.
  • Information by UniProt

Human PTP4A3 peptide (ab22906) 使用論文

ab22906 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"