製品の概要

製品の詳細

  • 由来Synthetic
  • アミノ酸配列
    • 生物種Human
    • 配列C-LKVKGEKSGLMST
    • 領域487 to 499

関連製品

特性

Our Abpromise guarantee covers the use of ab22909 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Blocking - Blocking peptide for Anti-PRPF31 antibody (ab2467)

  • 製品の状態Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

関連情報

  • 別名
    • DKFZp566J153
    • hPrp 31
    • hPrp31
    • NY BR 99
    • Pre mRNA processing factor 31
    • Pre mRNA processing factor 31 homolog
    • Pre mRNA processing factor 31 homolog (yeast)
    • Pre-mRNA-processing factor 31
    • Precursor mRNA-processing factor 31, S. cerevisiae, homolog of
    • Protein 61K
    • PRP 31
    • PRP31
    • PRP31 pre mRNA processing factor 31 homolog
    • PRP31 pre mRNA processing factor 31 homolog (yeast)
    • PRP31_HUMAN
    • PRPF 31
    • prpf31
    • RP 11
    • RP11
    • Serologically defined breast cancer antigen NY BR 99
    • Serologically defined breast cancer antigen NY-BR-99
    • SNRNP61
    • U4/U6 small nuclear ribonucleoprotein Prp31
    • U4/U6 snRNP 61 kDa protein
    see all
  • 機能Involved in pre-mRNA splicing. Required for U4/U6.U5 tri-snRNP formation.
  • 組織特異性Ubiquitously expressed.
  • 関連疾患Defects in PRPF31 are the cause of retinitis pigmentosa type 11 (RP11) [MIM:600138]. RP leads to degeneration of retinal photoreceptor cells. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well. RP11 inheritance is autosomal dominant.
  • 配列類似性Belongs to the PRP31 family.
    Contains 1 Nop domain.
  • ドメインInteracts with the snRNP via the Nop domain.
    The coiled coil domain is formed by two non-contiguous helices.
  • 細胞内局在Nucleus speckle. Nucleus > Cajal body. Predominantly found in speckles and in Cajal bodies.
  • Information by UniProt

Human PRPF31 peptide (ab22909) 使用論文

ab22909 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"