製品の概要

製品の詳細

  • 由来Synthetic
  • アミノ酸配列
    • アクセッション番号P25786
    • 生物種Human
    • 配列PADEPAEKADEPMEH
    • 領域249 to 263

関連製品

特性

Our Abpromise guarantee covers the use of ab4943 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Blocking

  • 製品の状態Liquid
  • 備考


    This peptide may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product and human proteasome 20S C2 subunit, catalog ab3325. Using a solution of peptide of equal volume and concentration to the corresponding antibody will yield a large molar excess of peptide (~ 70-fold) for competitive inhibition of antibody-protein binding reactions.

  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

関連情報

  • 別名
    • 30 kDa prosomal protein
    • HC 2
    • HC2
    • Macropain subunit C2
    • Macropain subunit nu
    • MGC14542
    • MGC14575
    • MGC14751
    • MGC1667
    • MGC21459
    • MGC22853
    • MGC23915
    • Multicatalytic endopeptidase complex subunit C2
    • NU
    • PROS 30
    • PROS-30
    • PROS30
    • Proteasome (prosome macropain) subunit alpha type 1
    • Proteasome alpha 1 subunit
    • Proteasome component C2
    • Proteasome nu chain
    • Proteasome subunit alpha type 1
    • Proteasome subunit alpha type I
    • Proteasome subunit alpha type-1
    • Proteasome subunit nu
    • Protein P30 33K
    • PSA1_HUMAN
    • PSC 2
    • PSC2
    • PSMA 1
    • psmA1
    see all
  • 機能The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. Mediates the lipopolysaccharide-induced signal transduction in the macrophage proteasome (By similarity). Might be involved in the anti-inflammatory response of macrophages during the interaction with C.albicans heat-inactivated cells.
  • 配列類似性Belongs to the peptidase T1A family.
  • 細胞内局在Cytoplasm. Nucleus.
  • Information by UniProt

Human Proteasome 20S C2 peptide (ab4943) 使用論文

This product has been referenced in:
  • Chu Y  et al. Alterations in lysosomal and proteasomal markers in Parkinson's disease: relationship to alpha-synuclein inclusions. Neurobiol Dis 35:385-98 (2009). Read more (PubMed: 19505575) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"