製品の概要

製品の詳細

  • 由来
    Synthetic
  • アミノ酸配列
    • アクセッション番号
    • 生物種
      Human
    • 配列
      An 18 amino acid synthetic peptide whose sequence is derived from human proteasome 20S beta 6 and amino acid residues 74-91 from frog protein. The sequence of this peptide is (amino to carboxy terminus): C(41)RSGSAADTQAV/IADAVTY(58).
    • 領域
      74 to 90

関連製品

特性

Our Abpromise guarantee covers the use of ab4947 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Blocking

  • 製品の状態
    Liquid
  • 備考


    This peptide may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product and human proteasome 20S beta 6, catalog ab3331. Using a solution of peptide of equal volume and concentration to the corresponding antibody will yield a large molar excess of peptide (~ 70-fold) for competitive inhibition of antibody-protein binding reactions.

  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

関連情報

  • 別名
    • DELTA
    • LMPY
    • Macropain delta chain
    • MGC5169
    • Multicatalytic endopeptidase complex delta chain
    • Proteasome (prosome macropain) subunit beta type 6
    • Proteasome beta 6 subunit
    • Proteasome catalytic subunit 1
    • Proteasome delta chain
    • Proteasome subunit beta 6
    • Proteasome subunit beta type 6
    • Proteasome subunit beta type-6
    • Proteasome subunit delta
    • Proteasome subunit Y
    • PSB6_HUMAN
    • PSMB6
    • PSY large multifunctional protease Y
    • Y
    see all
  • 機能
    The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This unit is responsible of the peptidyl glutamyl-like activity. May catalyze basal processing of intracellular antigens.
  • 配列類似性
    Belongs to the peptidase T1B family.
  • 細胞内局在
    Cytoplasm. Nucleus.
  • Information by UniProt

Human Proteasome 20S beta 6 peptide (ab4947) 使用論文

This product has been referenced in:
  • Wang Y  et al. Proteomic Analysis Implicates Dominant Alterations of RNA Metabolism and the Proteasome Pathway in the Cellular Response to Carbon-Ion Irradiation. PLoS One 11:e0163896 (2016). WB ; Mouse . Read more (PubMed: 27711237) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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