製品の概要

製品の詳細

  • 由来
    Synthetic
  • アミノ酸配列
    • 生物種
      Human
    • 配列
      C-QRLTPQVAASGGQS
    • 領域
      484 to 497

関連製品

特性

Our Abpromise guarantee covers the use of ab22848 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Blocking - Blocking peptide for Anti-PPP2R5B antibody (ab1366)

  • 製品の状態
    Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

関連情報

  • 別名
    • 2A5B_HUMAN
    • B56B
    • Beta isoform of regulatory subunit B56 protein phosphatase 2A
    • FLJ35411
    • PP2A B subunit B' beta isoform
    • PP2A B subunit B56 beta isoform
    • PP2A B subunit isoform B' beta
    • PP2A B subunit isoform B''-beta
    • PP2A B subunit isoform B56-beta
    • PP2A B subunit isoform PR61-beta
    • PP2A B subunit isoform R5-beta
    • PP2A B subunit PR61 beta isoform
    • PP2A B subunit R5 beta isoform
    • PPP2R5B
    • PR 61B
    • PR61B
    • Protein phosphatase 2 regulatory subunit B (B56) beta
    • Protein phosphatase 2 regulatory subunit B (B56) beta isoform
    • Protein phosphatase 2 regulatory subunit B' beta
    • Protein phosphatase 2 regulatory subunit B' beta isoform
    • Serine/threonine protein phosphatase 2A 56 kDa regulatory subunit beta isoform
    • Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform
    see all
  • 機能
    The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. The phosphorylated form mediates the interaction between AKT1 and PP2A phosphatase leading to dephosphorylation of AKT1 on the 'Thr-308' and 'Ser-373' residues.
  • 組織特異性
    Highest expression in brain.
  • 配列類似性
    Belongs to the phosphatase 2A regulatory subunit B56 family.
  • 細胞内局在
    Cytoplasm.
  • Information by UniProt

参考文献

ab22848 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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