Human PGK1 exon 1 ChIP Primer and Probe Set (ab85774)

製品の概要

  • 製品名Human PGK1 exon 1 ChIP Primer and Probe Set
  • 製品の概要

    Accession number: NM_000291.
    The HsPGK1 primers and probe can be used to quantify a control locus in chromatin immunoprecipitation (ChIP) assays with chromatin prepared from human cells.

    PGK1 (3-phosphoglycerate kinase 1) is a highly expressed housekeeping gene located on the X chromosome. The primers and probe are located in exon 1, within 1 kb of the transcription start site. In most female cells the locus is enriched with both active (e.g. Histone H3 K18 acetylation, see image with ab1191). and heterochromatic (e.g. Histone H3 K9 tri methylation, see image with ab8898) histone modification marks, as one copy of the gene undergoes X chromosome inactivation. In male cells, this locus is highly enriched with histone modifications associated with active gene transcription whereas it only shows low levels of heterochromatic histone modifications.

製品の特性

  • 機能In addition to its role as a glycolytic enzyme, it seems that PGK-1 acts as a polymerase alpha cofactor protein (primer recognition protein).
  • パスウェイCarbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5.
  • 関連疾患Defects in PGK1 are the cause of phosphoglycerate kinase 1 deficiency (PGK1D) [MIM:300653]. It is a condition with a highly variable clinical phenotype that includes hemolytic anemia, rhabdomyolysis, myopathy and neurologic involvement. Patients can express one or more of these manifestations.
  • 配列類似性Belongs to the phosphoglycerate kinase family.
  • 細胞内局在Cytoplasm.
  • Information by UniProt
  • 別名
    • Cell migration-inducing gene 10 protein
    • Epididymis secretory sperm binding protein Li 68p
    • HEL S 68p
    • MGC117307
    • MGC8947
    • MIG10
    • pgk1
    • PGK1_HUMAN
    • PGKA
    • Phosphoglycerate kinase 1
    • Primer recognition protein 2
    • PRP 2
    see all

Human PGK1 exon 1 ChIP Primer and Probe Set (ab85774) 使用論文

ab85774 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your response and your interest.

I can confirm that ab85774 (Human PGK1 exon 1 ChIP Primer and Probe Set) is available but we do not keep it in stock. As soon as we have the order, we will liaise with the lab to get the product....

Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"